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Effects of oral melatonin and gabapentin on tube placement in trachea for anaesthesia in patient posted for surgery


ABSTRACT: Intervention1: Oral study drugs 120 min before induction of anaesthesia: To study Haemodynamic responses to both drugs Control Intervention1: Tablet Gabapentin: Oral Gabapentin 800 mg in study group will be given 120 min before induction of anaesthesia in double blind manner. Placebo tablets 120 min before induction of anaesthesia in control group Control Intervention2: Tab Melatonin: Tab melatonin 6 mg orally 120 min before induction of anaesthesia Primary outcome(s): SBP,DBP,MAP,HRTimepoint: Just after intubation,1min,3min,5min,10min Study Design: Randomized, Parallel Group, Placebo Controlled Trial Method of generating randomization sequence:Computer generated randomization Method of allocation concealment:Sequentially numbered, sealed, opaque envelopes Blinding and masking:Participant, Investigator and Outcome Assessor Blinded

DISEASE(S): Calculus Of Gallbladder With Othercholecystitis,Calculus Of Kidney,Malignant Neoplasm Of Breast,Liver Disorders In Diseases Classified Elsewhere,Other Abdominal Hernia,Malignant Neoplasm Of Intestinal Tract, Part Unspecified,Asa Grade I And Ii, Normal Healthy Patient Posted For Elective Surgery,Perforation Of Intestine (nontraumatic)

PROVIDER: 2589334 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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