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Pilot study of chemopreventive effect of pioglitazone for colorectal cancer using aberrant crypt foci as a biomarker

ABSTRACT: Interventions: Oral administration of pioglitazone in 15mg daily. No administration of newly drug. Primary outcome(s): Observation of ACF using magnifying endoscopy Study Design: Parallel Randomized

DISEASE(S): Subjects With Aberrant Crypt Foci (acf)

PROVIDER: 2616758 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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DNA methylation analysisof KRAS mutated colorectal tumors and adjacent tissues from cancer patinets and KRAS mutated Aberrant Crypt Foci and matching normal crypts from healthy individuals by using RRBS

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