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Phase II trial of cetuximab plus irinotecan for FOLFOX and FOLFIRI-refractory patients with EGFR-positive advanced and/or metastatic colorectal cancer, evaluation of the safety and efficacy based on KRAS mutation status (T-CORE0801)

ABSTRACT: Interventions: cetuximab 400 mg/m2 given as 2 hours infusion for the first time, 250mg/m2 as 1 hour infusion for the second time or later. Irinotecan 100mg/m2 repeated every week followed by one week rest or Irinotecan 150mg/m2 repeated every two weeks. Primary outcome(s): response rate Study Design: Single arm Non-randomized

DISEASE(S): 3rd Line Or Later Therapy For Unresectable Advanced And/or Recurrent Colorectal Cancer

PROVIDER: 2617157 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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