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Study of the best epidural catheter location in ERAS protocol as perioperative medical care in rectum/sigmoid colon surgery

ABSTRACT: Interventions: Place the epidural catheter in the lower-thoracic level Place the epidural catheter in the mid-thoracic level Primary outcome(s): effect of postoperative analgesia and gastrointestinal recovery Study Design: Parallel Randomized

DISEASE(S): Colorectal Cancer

PROVIDER: 2620919 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Appropriate timing of urethral catheter removal in gastrointestinal surgery with epidural anesthesia: a randomized controlled trial

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A study to compare two different modes of pain relief techniques (continuous delivery of Lidocaine (a pain killer) through the vein and epidural infusion(delivery of pain killer around the layers of spinal cord) in all patients undergoing keyhole surgery for colon cancer

Project description:Intervention1: Lidocaine: Administered intravenously as 2mg/kg bolus followed by infusion at 2mg/kg/hr from the start of surgery till 30 minutes after surgery Control Intervention1: Thoracic Epidural Analgesia: Thoracic Epidural Catheter is inserted at T8-T9 level through which 0.25% Bupivacaine with 1mcg/cc Fentanyl is administered as an infusion for 48 hours post operatively Primary outcome(s): Postoperative pain score at various intervals using Visual Analogue Score(VAS)Timepoint: 2,4,8,12,24 hours post operative

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Genome wide analysis of thoracic spinal cord at 5 days after T9 hemisection injury.

Project description:The goal of this study is to elucidate the influence of hemisection injury at thoracic spinal cord (T9) and epidural electrical spinal stimulation (L2-S1) on transcriptome of injured thoracic spinal cord. mRNA profiles of spinal cord at 5 days-post injury with or without epidural electrical spinal stimulation (L2-S1) and before injury were generated. Our study represents the detailed analysis of transcriptomes of injured spinal cord with biologic replicates, generated by RNA-seq technology.

2020-05-11 | GSE138637 | GEO

RNA-sequencing of Imiquimod-induced rat skin treated with or without epidural lidocaine injection

Project description:We use back skin of WT SD rats, or imiquimod(IMQ)-induced psoraisis-like rat model treated with or without epidural injection of 1% lidocaine. We isolate total RNA for RNA-sequencing.

2020-03-13 | GSE146891 | GEO

Urinary catheter metagenome

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RNA-sequencing of Imiquimod-induced rat dorsal root ganglion (DRG) tissues treated with or without epidural lidocaine injection

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Urinary catheter metagenome BTTDD

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Confirmation of Thoracic Epidural Space by the presence of waveform and the depth analysis by ultrasound

Project description:Primary outcome(s): Documentation of epidural waveform through epidural needle and catheter. Timepoint: Immediately after loss of resistance

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Xenon Combined With Intraoperative Thoracic Epidural Analgesia

Project description:This is a monocentric study in 2 steps: A safety part to assess the feasibility of using Xenon in association with a thoracic epidural analgesia (TEA) with a sequential recruitment of 3, 6 or 9 patients according to predefined safety rules. The second part will randomly allocated patients (1:1) to receive TEA+Xenon or TEA+Desflurane. 28 patients will be enrolled and followed over 45 days.

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A clinical study to compare two techniques of pain relief(intravenous through blood route vs epidural through a catheter in back) after surgery for cancer treatment using reduction of tumour mass and chemotherapy at high temprature

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