Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Chemically assisted endoscopic submucosal dissection(CA-ESD) with a rubber band tissue traction device

ABSTRACT: Interventions: countertraction usings the rubber band traction device and using mesna as a submucosal injection solution. Primary outcome(s): Procedural success Study Design: Single arm Non-randomized

DISEASE(S): Esophageal Tumors, Gastric Tumors, Colorectal Tumors

PROVIDER: 2627563 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Endoscopic submucosal dissection for gastrointestinal tumor (esophagus,stomach,colon) using the traction device.

Project description:Interventions: countertraction usings the rubber band traction device Primary outcome(s): Procedural success Study Design: Single arm Non-randomized

| 2623559 | ecrin-mdr-crc

Application value of orthodontic rubber band traction technology in the cultivation of trainee of colorectal ESD

Project description:Interventions: Colorectal beginner ESD using the ORB group, colorectal beginner traditional ESD, expert group traditional ESD group:The orthodontic band was used for traction Primary outcome(s): Operating time Study Design: Parallel

| 41462 | ecrin-mdr-crc

A prospective study investigating the efficacy and safety of traction-band-assisted endoscopic closure for mucosal defect after colorectal endoscopic submucosal dissection: A multi-center trial (TBEC Trial)

Project description:Interventions: Traction-band-assisted endoscopic closure (TBEC) for mucosal defect after colorectal ESD Primary outcome(s): Complete closure of mucosal defect Study Design: Single arm Non-randomized

| 2740973 | ecrin-mdr-crc

Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction

Project description:transcriptional profile of both macrophages and endothelial end cells between three different lesion stages (uninjured control , upon macrophage arrival , and during macrophage traction). Examination of gene expression different in 2 cell types.

2016-02-23 | E-GEOD-78194 | biostudies-arrayexpress

Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction

2016-02-23 | GSE78194 | GEO

A randomized controlled trial about the efficacy of colorectal ESD using a scissors-type knife with traction device for early colorectal neoplasms

Project description:Interventions: Group A: C (Conventional)-ESD Group B: T (Traction)-ESD Primary outcome(s): the resected specimen area to the procedure time Study Design: Parallel Randomized

| 2655319 | ecrin-mdr-crc

Examination of the colorectal endoscopic submucosal dissection (ESD) with traction device which made easy to resect the colorectal tumors.

Project description:Interventions: endoscopic clip Primary outcome(s): Check for expended hours and success rate of en block resectionin of the ESD. Study Design: Single arm Randomized

| 2623525 | ecrin-mdr-crc

25 kDa band from HSPA1A immunoprecipitation

Project description:HSPA1A was immunoprecipitated from WT and TorsinKO HeLa cells. A band around 27 kDa was identified uniquely in TorsinKO samples and for identification, this band was extracted.

2022-08-25 | PXD036266 | Pride

Efficacy and Safety of Multi Loop Traction Device-assisted Colorectal Endoscopic Submucosal Dissection: A Multicenter, Randomized Clinical Trial

Project description:Interventions: 1) MLTD-ESD group Colorectal endoscopic submucosal dissection (ESD) is performed using the Multi Loop Traction Device (MLTD). The number of MLTD used in a single session is not limited. The conversion of the allocated therapeutic method is permitted. If the MLTD is ineffective for more than 10 minutes, the MLTD can be removed. 2) Conventional ESD group ESD is completed using a standard therapeutic strategy that does not involve the use of traction devices. The conversion of the allocated therapeutic method is permitted. The MLTD can be used if the endoscopist determines that the traction device has been required for more than 10 minutes. Primary outcome(s): Dissection speed (area resected [mm^2]/duration in minutes) Study Design: Parallel Randomized

| 2724553 | ecrin-mdr-crc

Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle

Project description:Muscle contraction is driven by the molecular machinery of the sarcomere. While the constituent components of the sarcomere are well characterized, it is less clear how the activity and turnover of sarcomeric proteins is regulated. In particular, phosphorylation is critical regulator of muscle function. Thus, identification of regulatory kinases is key to understanding the sarcomere function. Pathogenic variants in alpha kinase 3 (ALPK3) cause cardiomyopathy and musculoskeletal disease, but little is known about this atypical kinase. Here we show that ALPK3 localizes to the M-Band of the sarcomere and define the ALPK3-dependent phosphoproteome. ALPK3 deficiency disrupted sarcomeric organization and calcium kinetics in hPSC-derived cardiomyocytes and reduced force generation in cardiac organoids. Phosphoproteomic profiling identified ALPK3-dependant phospho-peptides that were enriched for sarcomeric components of the M-band and the ubiquitin-binding protein SQSTM1. Analysis of the ALPK3 interactome confirmed binding to M-band proteins including SQSTM1. Importantly, in hPSC-derived cardiomyocytes modeling ALPK3 deficiency and cardiomyopathic ALPK3 mutations, sarcomeric organization and M-band localization of SQSTM1 were abnormal. These data suggest ALPK3 has an integral role in maintaining sarcomere integrity and proteostasis in striated muscle. We propose this mechanism may underly disease pathogenesis in patients with ALPK3 variants.

2023-01-10 | GSE215304 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data