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Multicenter Phase II study to evaluate efficacy and safety of combination therapy with trastuzumab and pertuzumab in patients with HER2-positive metastatic colorectal cancer

ABSTRACT: Interventions: Combination therapy with trastuzumab and pertuzumab 1) Trastuzumab: 8 mg/kg (first dose), 6 mg/kg (second and subsequent doses), every 3 weeks 2) Pertuzumab: 840 mg (first dose), 420 mg (second and subsequent doses), every 3 weeks Both drugs will be intravenously administered. Primary outcome(s): Confirmed objective response rate (ORR) by investigators’ assessment Study Design: Single arm Non-randomized

DISEASE(S): Colorectal Cancer

PROVIDER: 2643096 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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