Research on required specifications of tele-monitoring system for oncology patients receiving ambulatory chemotherapy treatments
Ontology highlight
ABSTRACT:
DISEASE(S): Gastric Cancer, Colorectal Cancer, Breast Cancer
PROVIDER: 2652711 | ecrin-mdr-crc |
REPOSITORIES: ECRIN MDR
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Project description:Interventions: The Department of Health and Ageing has asked the Trans Tasman Radiation Oncology Group (TROG) to develop and pilot a radiation oncology register as part of the ANROTAT (TRP 11.A) project (http://www.ANZCTR.org.au/ACTRN12612000168853.aspx).
The ARORP will include the development and testing of a set of data variables to capture demographics, diagnosis, staging, surgical treatments, quality of Life, follow-up and radiotherapy intervention related data. A cross sectional feedback survey of participating centre staff authorised to enter data into the ARORP will be undertaken to assess the feasibility of the collection of the data items in routine practice as well as the web-based registration, the user manual and the register in general.
Data will be collected in two groups of patients;
1. Prospective ANROTAT (TRP 11.A) study participants at or after the first follow-up visit
2. Patients who are attending for their annual follow-up appointment (including ANROTAT (TRP 11.A) retrospective patients and NON-ANROTAT patients).
The data will be collected from the patients medical records, reports, RT plans and from QoL Questionniares. Patients are to be within 60months of completion of RT treament on registration, therefore the year range of the information collected will be from 2006-2012.
The study population are patients who have undergone;
- Image Guided Radiation Therapy (IGRT) or non-IGRT in patient with intermediate risk prostate cancer
- Intensity Modulated Radiation Therapy (IMRT) or 3DCRT in patients with prostate cancer (post-proctectomy)
- IMRT or 3DCRT in patients with nasophargeal cancer
- IMRT or 3DRT in patients with anal cancer.
This project will be open for registering patients from December 2011 t
Primary outcome(s): To assess the completeness and accuracy of the data collected using the online register system[End of project]
Study Design: Duration: Cross-sectional;Selection: Defined population;Timing: Both
| 2457886 | ecrin-mdr-crc
Project description:Targeted therapy drug monitoring in digestive oncology: Dosage of plasma levels of various multikinase inhibitors (MKI) in patients treated for advanced digestive cancer (gastrointestinal stromal tumor (GIST), metastatic colorectal cancer (mCRC), hepatocellular carcinoma (HCC), gastroenteropancreatic neuroendocrine tumor (gepNET), or pancreatic neuroendocrine tumor (pNET)), with the aim of determine the optimal dose adapted for each patient, in the future.
| 2739807 | ecrin-mdr-crc
Project description:To compare the burden of central line-associated bloodstream infections (CLABSIs) in ambulatory versus inpatient pediatric oncology patients, and identify the epidemiology of and risk factors associated with ambulatory CLABSIs.We prospectively identified infections and retrospectively identified central line days and characteristics associated with CLABSIs from January 2009 to October 2010. A nested case-control design was used to identify characteristics associated with ambulatory CLABSIs.We identified 319 patients with central lines. There were 55 ambulatory CLABSIs during 84,705 ambulatory central line days (0.65 CLABSIs per 1,000 central line days (95% CI 0.49, 0.85)), and 19 inpatient CLABSIs during 8,682 inpatient central line days (2.2 CLABSIs per 1,000 central lines days (95% CI 1.3, 3.4)). In patients with ambulatory CLABSIs, 13% were admitted to an intensive care unit and 44% had their central lines removed due to the CLABSI. A secondary analysis with a sub-cohort, suggested children with tunneled, externalized catheters had a greater risk of ambulatory CLABSI than those with totally implantable devices (IRR 20.6, P?<?0.001). Other characteristics independently associated with ambulatory CLABSIs included bone marrow transplantation within 100 days (OR 16, 95% CI 1.1, 264), previous bacteremia in any central line (OR 10, 95% CI 2.5, 43) and less than 1 month from central line insertion (OR 4.2, 95% CI 1.0, 17).In pediatric oncology patients, three times more CLABSIs occur in the ambulatory than inpatient setting. Ambulatory CLABSIs carry appreciable morbidity and have identifiable, associated factors that should be addressed in future ambulatory CLABSI prevention efforts.
| S-EPMC4559846 | biostudies-literature
Project description:RNA-seq for monitoring expression levels in mutants that do not anchor chromatin at the nuclear periphery.
2015-12-11 | GSE74067 | GEO
Project description:Monitoring and contamination incidence of gnotobiotic experiments performed in microisolator cages
| PRJEB41815 | ENA
Project description:This SuperSeries is composed of the following subset Series: GSE28606: Monitoring of functional gene responses to ERD (enhanced reductive dechlorination) from four TCE-contaminated sites GSE28608: Monitoring of functional gene responses to biostimulation from a TCE-contaminated site Refer to individual Series
2012-04-02 | E-GEOD-28609 | biostudies-arrayexpress
Project description:BackgroundWe describe the implementation of enhanced recovery after surgery (ERAS) programs designed to minimize postoperative nausea and vomiting (PONV) and pain and reduce opioid use in patients undergoing selected procedures at an ambulatory cancer surgery center. Key components of the ERAS included preoperative patient education regarding the postoperative course, liberal preoperative hydration, standardized PONV prophylaxis, appropriate intraoperative fluid management, and multimodal analgesia at all stages.MethodsWe retrospectively reviewed data on patients who underwent mastectomy with or without immediate reconstruction, minimally invasive hysterectomy, thyroidectomy, or minimally invasive prostatectomy from the opening of our institution on January 2016 to December 2018. Data collected included use of total intravenous anesthesia (TIVA), rate of PONV rescue, time to first oral opioid, and total intraoperative and postoperative opioid consumption. Compliance with ERAS elements was determined for each service. Quality outcomes included time to first ambulation, postoperative length of stay (LOS), rate of reoperation, rate of transfer to acute care hospital, 30-day readmission, and urgent care visits ≤30 days.ResultsWe analyzed 6781 ambulatory surgery cases (2965 mastectomies, 1099 hysterectomies, 680 thyroidectomies, and 1976 prostatectomies). PONV rescue decreased most appreciably for mastectomy (28% decrease; 95% confidence interval [CI], -36 to -22). TIVA use increased for both mastectomies (28%; 95% CI, 20-40) and hysterectomies (58%; 95% CI, 46-76). Total intraoperative opioid administration decreased over time across all procedures. Time to first oral opioid decreased for all surgeries; decreases ranged from 0.96 hours (95% CI, 2.1-1.4) for thyroidectomies to 3.3 hours (95% CI, 4.5 to -1.7) for hysterectomies. Total postoperative opioid consumption did not change by a clinically meaningful degree for any surgery. Compliance with ERAS measures was generally high but varied among surgeries.ConclusionsThis quality improvement study demonstrates the feasibility of implementing ERAS at an ambulatory surgery center. However, the study did not include either a concurrent or preintervention control so that further studies are needed to assess whether there is an association between implementation of ERAS components and improvements in outcomes. Nevertheless, we provide benchmarking data on postoperative outcomes during the first 3 years of ERAS implementation. Our findings reflect progressive improvement achieved through continuous feedback and education of staff.
| S-EPMC8568332 | biostudies-literature
Project description:Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.
2020-06-16 | GSE100150 | GEO
Project description:ObjectivePediatric oncology patients are frequently managed with central lines as outpatients, and these lines confer significant morbidity in this immune-compromised population. We aimed to investigate whether a multidisciplinary, central line maintenance care bundle reduces central line-associated bloodstream infections (CLABSIs) and bacteremias in ambulatory pediatric oncology patients.MethodsWe conducted an interrupted time-series study of a maintenance bundle concerning all areas of central line care. Each of 3 target groups (clinic staff, homecare agency nurses, and patient families) (1) received training on the bundle and its importance, (2) had their practice audited, and (3) were shown CLABSI rates through graphs, in-service training, and bulletin boards. CLABSI and bacteremia person-time incidence rates were collected for 23 months before and 24 months after beginning the intervention and were compared by using a Poisson regression model.ResultsThe mean CLABSI rate decreased by 48% from 0.63 CLABSIs per 1000 central line days at baseline to 0.32 CLABSIs per 1000 central line days during the intervention period (P = .005). The mean bacteremia rate decreased by 54% from 1.27 bacteremias per 1000 central line days at baseline to 0.59 bacteremias per 1000 central line days during the intervention period (P < .001).ConclusionsImplementation of a multidisciplinary, central line maintenance care bundle significantly reduced CLABSI and bacteremia person-time incidence rates in ambulatory pediatric oncology patients with central lines. Further research is needed to determine if maintenance care bundles reduce ambulatory CLABSIs and bacteremia in other adult and pediatric populations.
| S-EPMC3813391 | biostudies-literature
Project description:RNA-seq for monitoring expression levels in mutants that do not anchor chromatin at the nuclear periphery. RNA-seq of depleted rRNA samples of early embryo extracts for three different genotypes: wild-type, cec-4_delta and met-2 set-25_delta_delta, in two independent biological replicas
2015-12-11 | E-GEOD-74067 | biostudies-arrayexpress