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Preoperative less painful mechanical bowel preparation in elective resection colorectal cancer surgery: a multicenter randomized non-Inferiority study

ABSTRACT: Interventions: mOAMBP group(sodium picosulfate hydrate + Kanamycin, Metronidazole) (combined drug) Kanamycin 250mg 12C x3(after lunch, dinner, and before bedtime) and Metronidazole 250mg 6C x3(after lunch, dinner, and before bedtime) per oral the day before surgery (research drug) (1 day method) sodium picosulfate hydrate 75.0mg(after hospitalization) per oral or (2 days method) sodium picosulfate hydrate 37.5 mg two days before surgery(after hospitalization) and 37.5 mg the day before surgery(morning) per oral OAMBP group(PEG/PEG based solution + Kanamycin, Metronidazole) (combined drug) Kanamycin 250mg 12C x3(after lunch, dinner, and before bedtime) and Metronidazole 250mg 6C x3(after lunch, dinner, and before bedtime) per oral the day before surgery (control drug) (1 day method) 1 pack of PEG/ PEG based solution the day before surgery(after hospitalization) per oral (2 days method) 1 pack of PEG/ PEG based solution two days before surgery(after hospitalization) per oral Primary outcome(s): Incidence of SSI Study Design: Parallel Randomized

DISEASE(S): Left Colon Cancer, Rectal Cancer

PROVIDER: 2659463 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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