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Analgesic effects of quaratus lumborum block and transversus abdominis plane block after laparoscopic radical resection of colorectal cancer

ABSTRACT: Interventions: 1:quadratus lumborum block;2:transversus abdominis plane block Primary outcome(s): morphine consumption at postoperative different time points Study Design: Randomized parallel controlled trial

DISEASE(S): Colorectal Cancer

PROVIDER: 2664504 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Ultrasound-guided Quadratus Lumborum Block versus Ultrasound-guided Transversus Abdominis Plane Block for perioperative pain control in open colorectal surgery

Project description:Interventions: QLB group:ultrasound-guided quadratus lumborum block was performed;TAP group:preoperative ultrasound-guided transversus abdominis plane block was performed Primary outcome(s): Sufentanil dosage Study Design: Parallel

| 2684324 | ecrin-mdr-crc

Effects of quaratus lumborum block versus transversus abdominis plane block on enhanced recovery after laparoscopic radical resection of colorectal cancer : A prospective randomized controlled study

Project description:Interventions: QL:Bilateral quaratus lumborum block with 0.375% ropivacaine 20ml;TAP:Bilateral transversus abdominis plane block with 0.375% ropivacaine 20ml Primary outcome(s): Visual analogue pain scale (VAS);intraoperative remifentanil consumption Study Design: Randomized parallel controlled trial

| 2675831 | ecrin-mdr-crc

Comparison of the postoperative analgesic effect of transversus abdominis plan block and quadratus lumborum block: A prospective randomized study.

Project description:Background and aimsIn this study, we aimed to compare the transversus abdominis plan block (TAP) and quadratus lumborum block (QL) efficacy for postoperative analgesia in patients undergoing varicocelectomy under spinal anesthesia.MethodsAmerican Society of Anesthesiologists (ASA) 1 and 2 patients, aged 18-45 years, who underwent varicocelectomy operation under elective conditions, were included. Eighty patients were divided into three groups as TAP group, QL group, and control group by prospective randomization. The patients were operated under spinal anesthesia. At the end of the operation, TAP was applied to the TAP group with a posterior approach using ultrasound (USG) in the supine position. To the QL group, the patient was placed in the lateral decubitus position and the lateral QL was applied via USG. No block type was applied to the control group. Patient-controlled analgesia (PCA) device containing tramadol was administered intravenously at the end of the surgery in all groups. Visual analogue scale (VAS) score was questioned at 0, 2, 4, 6, 8, 10, 12, 18, 24 h in the follow-up of the patients. Intravenous 1 g paracetamol was given over VAS 4. PCA usage time and usage amounts were recorded.ResultsAs a result of comparing the groups according to the VAS scores at all hours were significantly different between the three groups (p < 0.001). There was a significant difference between the groups when comparing the number of PCA bolus administrations (p < 0.001). TAP and QL blocks significantly reduced the number of PCA bolus when compared with the control group (p < 0.001) but the number of PCA bolus was found to be similar between TAP and QL blocks (p > 0.05).ConclusionTAP and QL, which are administered to evaluate the effectiveness of postoperative analgesia in patients undergoing varicocelectomy under spinal anesthesia, are both effective in reducing pain scores and the amount of analgesia consumption.

| S-EPMC9358534 | biostudies-literature

Bilateral anterior quadratus lumborum block at lateral supra-arcuate ligament versus bilateral lateral quadratus lumborum block for analgesia in laparoscopic resection of colorectal cancer

Project description:Interventions: Experimental group1:Bilateral anterior quadratus lumborum block at lateral supra-arcuate ligament;Experimental group2:bilateral lateral quadratus lumborum block Primary outcome(s): the total consumption of sufentanil in 24 hours Study Design: Parallel

| 2760239 | ecrin-mdr-crc

Analgesic efficacy of ultrasound-guided transversus abdominis plane block and lateral approach quadratus lumborum block after laparoscopic appendectomy: A randomized controlled trial.

Project description:BackgroundLaparoscopic appendectomy is the most performed emergency surgical technique worldwide. Transversus abdominis plane (TAP) blocks, which are easier to achieve with ultrasound, are frequently used in multimodal analgesia techniques for this surgery. Quadratus lumborum (QL) block has become a standard block, first used in gynecological and other abdominal surgeries. This study was planned to compare the analgesic efficacy of ultrasound-guided QL and TAP blocks for postoperative analgesia after laparoscopic appendectomy.Materials and methodsA total of 136 patients aged 18-65 years who underwent laparoscopic appendectomy were randomized and divided into two groups. A volume of 40 ml of local anesthetic containing 0.375% bupivacaine was administered for block applications in group TAP (n = 68) and group QL (n = 68). In addition, a patient-controlled analgesia device was used to administer bolus tramadol hydrochloride at a dose of 10 mg to relieve pain in the postoperative period. Postoperative opioid consumption of patients was recorded as the primary outcome and pain scores (1, 6, 12, 18, 24 h) as the secondary outcome.ResultsBoth groups were statistically similar in demographic and surgical data. There were no statistically significant differences between the groups over 24 h in terms of intraoperative remifentanil consumption (p = 0.584), postoperative cumulative opioid consumption (p = 0.807), and pain scores. No complications were observed in either group related to the block.ConclusionUltrasound-guided lateral approach QL block may provide adequate analgesia efficacy in patients undergoing laparoscopic appendectomy, like TAP block, and may be included in multimodal analgesia in pain control.

| S-EPMC9289327 | biostudies-literature

Analgesia of Erector Spinae Plane Block Versus Quadratus Lumborum Block

Project description:Colorectal cancer is the third most common cancer worldwide. These patients usually undergo open surgical resection of cancer under general anaesthesia. The aim of this study is to detect whether the Erector spinae plan block or Quadratus lumborum block will provide the most ideal analgesia for these patients. Erector spinae plan block is a novel analgesic technique that provides both visceral and somatic analgesia due to its communication with the paravertebral space. Quadratus lumborum block is a truncal nerve block usually used for intra-abdominal surgeries. Ultrasound guidance increases the accuracy and safety of both techniques. A local anaesthetic mixture of Bupivacaine 0.25% and dexamethasone will be used for both techniques.

| 2294293 | ecrin-mdr-crc

Analgesic effects and distribution of cutaneous sensory blockade of quadratus lumborum block type 2 and posterior transversus abdominis plane block: an observational comparative study.

Project description:BackgroundThe posterior transversus abdominis plane block (TAPB) and quadratus lumborum block (QLB) were developed for postoperative pain control after lower abdominal surgery. However, there is little data regarding their effects. Their analgesic effects and the distribution of the cutaneous sensory blockade were observed in patients undergoing laparoscopic gynecologic surgery.MethodsAfter an induction of general anesthesia, patients alternately received bilateral ultrasound-guided QLB type 2 (QLB2) or posterior TAPB using 20 ml of 0.375% levobupivacaine on each side. The measurements included visual analogue pain scores (VAS), cutaneous sensory blockade in each dermatome, demands for postoperative analgesics, and complications for up to 48 h after the block. Our primary endpoint was VAS at 24 h after the block.ResultsForty patients completed the study. The VAS at rest was significantly lower after QLB2 than that after TAPB at 48 h, but not at 24 h. Neither group differed in VAS when coughing at any point in time. Postoperative demands for fentanyl and other analgesics also did not differ for either block. The majority of injections produced a cutaneous sensory blockade in the T11 and T12 dermatomes in both groups. The median number of dermatomes blocked was limited to three dermatomes after either block. No severe complication related to either block was observed.ConclusionsThe analgesic effects of QLB2 and posterior TAPB did not differ in patients undergoing laparoscopic gynecologic surgery. The cutaneous sensory blockade produced was limited to three dermatomal levels in the majority of patients. However, these findings need to be confirmed through a larger comparative study.

| S-EPMC7403112 | biostudies-literature

Lateral Quadratus Lumborum Block versus Transversus Abdominis Plane Block in Laparoscopic Surgery: A Randomized Controlled Study.

Project description:BackgroundAfter laparoscopic abdominal surgery, we aim to evaluate the analgesic efficiency of US-directed bilateral transversus abdominis plane block (TAPB) and quadratus lumborum block (QLB).Methods50 patients aged 18-60 years listed for elective laparoscopic abdomen operation were registered in this study. Cases were randomly allocated into two similar groups: TAPB and QLB groups. The first outcome was the growing morphine consumption on the 1st day postoperatively. The second outcome involved VAS score, first analgesic necessities, and any postoperative complications. Statistical analysis was done with the 2-sample t-test, and Mann-Whitney U testing was utilized to compare medians for skewed end points. Qualitative data were introduced as numbers and percentages, and chi-squared testing was utilized to determine the significance.ResultsThe median cumulative morphine consumptions on the 1st day were high significantly in the TAPB group than in the QLB group (6 mg [6, 9] vs. 3 mg [3, 6], p value ≤0.0001]). The QLB group showed an increase in the median of the time to the first analgesic request in comparison with the TAPB group (17 hours [12, 24] vs. 8 hours [6, 24], p ≤ 0.001). In addition, on the 1st day, the mean VAS scoring at rest was lower in the QLB group.ConclusionIn comparison to the TAPB, the QL block delivers more successful pain relief, has an extended period of analgesic actions, extends interval to the 1st analgesic necessity, is accompanied with lesser morphine consumptions, and may be utilized in multimodal analgesia and opioid-sparing regimens after that laparoscopic operation. This trial is registered with NCT04553991.

| S-EPMC8979728 | biostudies-literature

Effects of quadratus lumborum block on enhanced recovery after surgery in patients following laparoscopic radical resection of colorectal cancer

Project description:Interventions: contorl:bilateral quadratus lumborum block with 0.9 normal saline (20-30ml) on each side;QLB:bilateral quadratus lumborum block with 0.33 % ropivacaine (20-30ml) on each side Primary outcome(s): sufentanil consumption;Visual analogue pain scale (VAS) Study Design: Randomized parallel controlled trial

| 2675735 | ecrin-mdr-crc

Effects of ultrasound-guided quadratus lumborum block on perioperative pain control and outcome in laparoscopic radical resection of colorectal cancer

Project description:Interventions: Control group:patient control intravenous analgesia;Experimental group 1:Combination of ultrasound-guided anterior quadratus lumborum block 2mg/kg and patient control intravenous analgesia;Experimental group 2:Combination of ultrasound-guided anterior quadratus lumborum block 3mg/kg and patient control intravenous analgesia Primary outcome(s): visual analog scale, VAS Study Design: Parallel

| 2690168 | ecrin-mdr-crc

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