Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Comparison of Three Different Liquid Therapy in Colorectal Surgery

ABSTRACT: Interventions: R group (restricted fluid treatment group):Rrestricted fluid ;W group (Wash-out liquid treatment group):Open fluid input and furosemide are given ;Group G (Goal-directed fluid therapy group):Goal-directed fluid therapy Primary outcome(s): blood pressure;Heart Rate;IL-6;CRP;TNF-a Study Design: Randomized parallel controlled trial

DISEASE(S): Colorectal Cancer

PROVIDER: 2676166 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Effect of goal-directed fluid therapy based on plasma colloid osmotic pressure on the postoperative pulmonary complications of elderly patients undergoing major abdominal surgery

Project description:Interventions: Group 1:Total fluid input = physiological requirement + preoperative cumulative loss + continuing loss + third space loss + compensatory volume expansion;Group 2:Goal-directed fluid therapy based on stroke volume variation;Group 3:Goal-directed fluid therapy based on stroke volume variation and plasma colloid osmotic pressure Primary outcome(s): Indicators of changes in lung function;Postoperative pulmonary complications occurring within 7 days after surgery;Lung injury score Study Design: Parallel

| 2705802 | ecrin-mdr-crc

Application of GDFT combined with low dose metaraminol in elderly patients undergoing laparoscopic radical resection of colorectal cancer

Project description:Interventions: Group C:Routine infusion ; Group G:Goal-directed fluid therapy;Group GM:goal-directed fluid therapy combined with low-dose metaraminol Primary outcome(s): Mean arterial pressure;Cardiac output;Heart index;Stroke volume Study Design: Randomized parallel controlled trial

| 2680686 | ecrin-mdr-crc

Effects of Goal-directed Fluid Therapy guided by SVV on intestinal barrier function in patients undergoing colon cancer surgery

Project description:Interventions: Group GDFT:Goal-directed fluid therapy;Group control:Traditional fluid therapy Primary outcome(s): IFABP;D-lactic acid;SVV;CI;Q-40 score Study Design: Parallel

| 2700173 | ecrin-mdr-crc

Effect of goal-directed fluid therapy on glycocalyx in elderly patients with colorectal cancer and its mechanism

Project description:Interventions: control group:nothing;treatment group:goal-directed fluid therapy Primary outcome(s): TNF-a;heparan sulfate;syndecan-1 Study Design: Parallel

| 2741182 | ecrin-mdr-crc

Project description:Dimethyl itaconate ameliorates goal-directed behavior in Toxoplasma gondii infected mice

| PRJNA801463 | ENA

Control ChIP-seq from whole organism (ENCSR040UNE)

Project description:Input control for ChIP-seq on transgenic flies expressing crp-eGFP fusion proteins. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2024-02-27 | GSE257006 | GEO

Control ChIP-seq from whole organism (ENCSR080DBI)

2024-02-27 | GSE257311 | GEO

Expression analysis, A. actinomycetemcomitans wild type (JP2) vs CRP deletion mutant both grown anaerobically.

Project description:The goal of this analysis is to define the anaerobic regulon for the global transcription factor CRP (catabolite repressor protein) in the periodontal pathogen Aggregatibacter actinomycetemcomitans. The objectives were met by comparing the mRNA profile of a wild type strain, JP2, to that of an isogenic mutant deleted of the CRP gene. Both strains were grown anaerobically.

2011-06-01 | GSE25459 | GEO

Arabidopsis Apoplastic Fluids Contain sRNA- and Circular RNA-Protein Complexes That Are Located Outside of Extracellular Vesicles

Project description:The extracellular space within plant leaves is called the apoplast, and functions as a key battlefield between plants and pathogens. Previously, we have shown that apoplastic wash fluid purified from Arabidopsis leaves contains small RNAs (sRNAs). To investigate whether these RNAs are encapsulated inside extracellular vesicles (EVs), we treated EVs isolated from Arabidopsis leaves with the protease trypsin and RNase A, which should degrade RNAs located outside of EVs, but not those located inside. These analyses revealed that apoplastic RNAs are mostly located outside of EVs and are associated with proteins. Additional analyses of these extracellular RNAs (exRNAs) revealed that they are made up both sRNAs and long non-coding RNAs (lncRNAs), including circular RNAs (circRNAs). We also found that exRNAs are highly enriched in the post-transcriptional modification N6-methyladenine (m6A). Consistent with this, we identified a putative m6A-binding protein in apoplastic wash fluids, GLYCINE-RICH RNA BINDING PROTEIN 7 (GRP7), as wells as the small RNA-binding protein ARGONAUTE2 (AGO2). These two proteins co-immunoprecipitated with each other, and with lncRNAs, including circRNAs. Mutation of GRP7 or AGO2 caused changes in both the sRNA and lncRNA content of apoplastic wash fluid, suggesting that these proteins contribute to the secretion and/or stabilization of exRNAs.

2022-04-18 | GSE183867 | GEO

Arabidopsis Apoplastic Fluid Contains sRNA- and Circular RNA-Protein Complexes that Are Located Outside Extracellular Vesicles

2022-04-18 | GSE185133 | GEO