Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of multi-mode preanalgesia on gastrointestinal dysfunction and postoperative outcome in patients undergoing laparoscopic colorectal surgery

ABSTRACT: Interventions: Experimental group:Transabdominal muscle plane block was performed before anesthesia induction + Flurbiprofen 1mg/kg was given before skin cutting + Oxycodone was given at 0.1mg/kg before skin cutting + Oxycodone was administered at 0.1mg/kg before surgery;control group:Sufentanil was given at 0.1ug/kg before peeling + Before the operation, flurbiprofen was given 1mg/kg + Sufentanil was administered at 0.1ug/kg before surgery + TAPB was performed postoperatively Primary outcome(s): I-FEED;Complications of other organs after operation Study Design: Parallel

DISEASE(S): Colorectal Cancer, Colon Cancer

PROVIDER: 2688997 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

3' RNA sequencing of the mouse cortex at P6 following MMS and/or LPS

Project description:Mice were given PBS or LPS (1mg/kg) with or without subsequent MMS. 3' RNA sequencing was carried out on whole cortical tissue from P6.

2021-06-01 | GSE157184 | GEO

Bis-(2-chloroethyl) sulfide exposure time course and dose response in the rat lung

Project description:Male Sprague-dawley rats were exposed to saline, isopropyl alcohol, 1mg/kg, 3mg/kg or 6 mg/kg sulfur mustard for 30 min, 1 hr, 3 hr, 6 hr, or 24 hr before analysis of lung tissue by oligonucleotide array analysis. Keywords = sulfur mustard Keywords = rat Keywords = lung Keywords = bis-(2-chloroethyl) sulfide Keywords: ordered

2004-12-20 | GSE1888 | GEO

Transcription profiling of lung tissue of male Sprague Dawley rats after exposure to saline, isopropyl alcohol and sulfur mustard for 30 min, 1 hr, 3 hr, 6 hr, or 24 hr

Project description:Male Sprague-Dawley rats were exposed to saline, isopropyl alcohol, 1mg/kg, 3mg/kg or 6 mg/kg sulfur mustard for 30 min, 1 hr, 3 hr, 6 hr, or 24 hr before analysis of lung tissue by oligonucleotide array analysis.

2007-09-14 | E-GEOD-1888 | biostudies-arrayexpress

Effects of dexmedetomidine combined with epidural anesthesia on intestinal function and postoperative outcomes of patients undergoing laparoscopic colorectal cancer surgery

Project description:Interventions: Control group (CON group):Intravenous and inhalation combined anesthesia, equal amount of normal saline; Sufentanil PCIA.;Dexmedetomidine group (DEX group):Dexmedetomidine group (DEX group): intravenous anesthesia was assisted by intravenous of DEX with the loading dose of 0.5~1.0 microgram/kg completed within 10 minutes and maintenance infusion of 0.5~1.0 microgram /kg/h until the end of the operation. Sufentanil + DEX to implement PCIA.; Epidural group (EP group):Intravenous Inhalation Combined with epidural anesthesia, ropivacaine + sufentanil PCEA;DEX + EP group:Intravenous anesthesia assisted by intravenous DEX combined with epidural anesthesia, ropivacaine + DEX PCEA. Primary outcome(s): Peristalsis time after operation;Oral feeding time after operation Study Design: Parallel

| 47743 | ecrin-mdr-crc

Exploring the potential mechanism of Zhuanggu Zhitong Capsule in the treatment of osteoporosis in ovariectomized rats based on the transcriptome

Project description:Objective: To analyze the differentially expressed genes and related pathways of Zhuanggu Zhitong Capsule (ZGZTC) in the treatment of osteoporosis in ovariectomized rats based on transcriptome sequencing. Methods: Eighteen SD female rats were randomly divided into sham operation group, model group and ZGZTC group, each with 6 rats. Intervention was started 1 week after the model was established. The experimental group was given ZGZTC (567mg/kg), and the sham operation group and model group were given (1ml/150g) volume of distilled water, once a day for 13 consecutive weeks. On the second day after the last administration, samples were taken and blood was collected from the abdominal aorta to prepare the corresponding group of serum. RNA-Seq sequencing was performed to screen differentially expressed genes and KEGG function Annotation analysis and GO enrichment analysis.

2022-05-09 | GSE202395 | GEO

Effects of neonatal dosing of SERMs on CD1 mouse uterine gene expression at 3 months

2005-12-02 | GSE3625 | GEO

Effects of neonatal dosing of SERMs on CD1 mouse uterine gene expression at 3 months

Project description:Tamoxifen, a selective estrogen receptor modulator (SERM), is an effective treatment for breast cancers. In the CD-1 mouse model, neonatal oral dosing with tamoxifen leads to the development of adenomyosis. Both 4-hydroxyestradiol and tamoxifen can form DNA-reactive metabolites and may be involved in carcinogenesis of the uterus. After comparing the uterotrophic response of several SERMs the maximal uterotrophic doses of estradiol (100mg/kg) 4-hydroxyestradiol (385mg/kg) and tamoxifen (250mg/kg) were determined. Maximal uterotrophic doses were given orally to newborn CD-1 mice on days 1 â 4 after birth and gene and pathological changes examined in the uterus at 3 months after dosing. ERKOa knockout mice were dosed orally with tamoxifen (1mg/Kg) on days 1 â 4 after birth and uterine gene expression compared with CD-1 mice. Dosing groups: Estradiol (E2): 100mg/Kg 4-hydroxyestradiol (4OHE2): 385mg/Kg Tamoxifen : 250mg/Kg ERKO mice dosed with tamoxifen (1mg/Kg) 4 dosed animals and 4 controls for each treatment group. Uteri removed at 3 months after dosing and total RNA extracted. Controls were pooled. RNA labelling, hybridisation and analysis of fluorescence was carried out as described by Turton et al (2001). Cy3/Cy5 dye swap labelling was carried out on samples from each animal. Reference: Turton NJ et. al. (Oncogene (2001) 20, 1300-1306

2010-06-30 | E-GEOD-3625 | biostudies-arrayexpress

Transcriptomics analysis of the livers of old mice treated with Ouabain

Project description:Methods: Liver mRNA profiles of 7 weeks old wild-type (WT) and 24 months old mice treated with Vehicle or Ouabain (1mg/Kg)

2019-09-03 | GSE122080 | GEO

Myocardial KLF15 epigenomic changes with single ZT0 prednisone pulse

Project description:this dataset encompasses the cardiac KLF15 epigenomic changes elicited in 4-month-old mice with a single ZT0 prednisone (1mg/kg i.p.) injection

2024-01-31 | GSE254114 | GEO

Myocardial GR epigenomic changes with single ZT0 prednisone pulse

Project description:this dataset encompasses the cardiac GR epigenomic changes elicited in 4-month-old mice with a single ZT0 prednisone (1mg/kg i.p.) injection

2024-01-14 | GSE252856 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data