Browse
Submit Data
Databases
API
Help

Dataset Information

7 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expiratory Muscle Training Versus Incentive Spirometry After Colorectal Surgery

ABSTRACT: The aim of this study was to compare the effects of expiratory muscle training (EMT) and incentive spirometry (IS) in addition to conventional pulmonary rehabilitation after colorectal surgery. Twenty-four individuals (13 male) undergoing colorectal surgery were included. They were randomly divided into two groups. In addition to conventional chest physiotherapy, group 1 was performed EMT (n=12), group 2 was performed deep breathing exercises with incentive spirometry (IS) in postoperative period. Respiratory muscle strength, functional capacity, levels of movement and independence, and postoperative pulmonary complications (PPC) were evaluated. Length of stay in hospital (LOS) was recorded.

DISEASE(S): Pulmonary Rehabilitation,Colorectal Cancer,Colorectal Neoplasms

PROVIDER: 2710214 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Prehabilitation in colorectal cancer patients scheduled for elective colorectal resection

Project description:Interventions: The primary endpoint of this study is the number of postoperative complications within 30 days after elective colorectal surgery. In this study, 42 patients will receive 4 weeks of physiotherapy before surgery. The physiotherapy consists of one hour, high intensity, cardiopulmonary training combined with periphery muscle training, three times a week. The patients will train on Monday, Wednesday and Friday. The training contains cardio-training and muscle strength training (arm and legs) and will be adjusted to the cardiopulmonary reserve of the individual patient, based upon the results of the cardiopulmonary exercise test and the spirometry. The training will be performed under the guidance of a physiotherapist in a private physiotherapy practice in the catchment of the Medisch Spectrum Twente Hospital. Also the patient fulfill home exercises, like walking or cycling and climbing up a stairs, for two times a week for at least 30 minutes at a time, unsupervised, on a moderate level of intensity. The control group of 42 patients will receive regular health care, without physiotherapy or home exercises. All patients perform a CPET twice. One CPET at the beginning of the study (before the intervention) and one CPET after 4 weeks. The anaerobic threshold will be measured in the intervention group (with physiotherapy) and in the control group (without physiotherapy). Both groups will undergo colorectal surgery. The postoperative complications will be recorded within 30 days after surgery by using the Clavien-Dindo classification. Primary outcome(s): Postoperative complications (pulmonary, renal, gastrointestinal, infective, cardiovascular, neurological, haematology, pain, wound) within 30 days after surgery in group A and B. Study Design: Randomized controlled trial, Open (masking not used), Placebo, Parallel

| 18233 | ecrin-mdr-crc

The lung protective effect of driving pressure-guided pulmonary protective ventilation combined deep neuromuscular block in patients undergoing laparoscopic surgery for colorectal cancer

Project description:Intervention group:driving pressure-guided pulmonary protective ventilation combined deep neuromuscular block;Control group:normal pulmonary ventilation combined normal neuromuscular block Primary outcome(s): Postoperative pulmonary complications;Muscle relaxation monitoring Study Design: Parallel

| 40239 | ecrin-mdr-crc

Serum proteomic for pulmonary infection after pediatric congenital heart surgery

Project description:To explore serum proteins associated with postoperative pulmonary infection in children with CHD, a total of 98 serum samples collected from the 23 patients before and after surgery were subjected to proteomic analysis

2024-05-21 | PXD051904 | Pride

Evaluation of pulmonary complications during laparoscopic surgery in patients with protective mechanical ventilation combined deep neuromuscular block

Project description:Interventions: Group 1:Lung-protective ventilation combined with deep neuromuscular blockade and low pneumoperitoneum pressure;Group 2:Conventional pulmonary ventilation combined with moderate NMB (neuromuscular blockade) and conventional pneumoperitoneum pressure Primary outcome(s): Postoperative Pulmonary Complications Study Design: Parallel

| 35013 | ecrin-mdr-crc

The PROtective Ventilation Using Open Lung Approach Or Not Trial

Project description:Postoperative Pulmonary Complications (PPC) are very common. It severely affects postoperative recovery, particularly in the abdominal surgery. Patients with laparoscopic resection of colorectal cancer generally have a higher age and decreased lung function reserve. At the same time, they prone to developing atelectasis due to the effects of pneumoperitoneum pressure. Therefore, they are a high-risk group of respiratory insufficiency and PPC. Mechanical ventilation with a low tidal volume is a routine in clinic nowadays. However, this conventional strategy will also result in atelectasis formation. Therefore, it may deteriorate the vulnerable lung function of patients undergoing laparoscopic resection of colorectal cancer. Patients with Acute Lung Injury or Acute Respiratory Distress Syndrome (ALI/ARDS) could benefit from the "open lung approach", including the use of positive end-expiratory pressure (PEEP) and recruitment maneuvers (RMs). Whether a lung protective mechanical ventilation strategy with medium levels of PEEP and repeated RMs, the "open lung approach", protects against respiratory insufficiency and PPC during laparoscopic resection of colorectal cancer is uncertain. The present study aims at comparing the effects of "open lung approach" mechanical ventilation strategy and conventional mechanical ventilation strategy in PPC, extra-pulmonary complications, length of hospital stay, biomarkers of lung injury and changes of respiratory function in patients undergoing general anesthesia for laparoscopic resection of colorectal cancer.

| 2244915 | ecrin-mdr-crc

RNA sequencing of healthy and diseased (idiopathic pulmonary hypertension) human pulmonary artery smooth muscle cells

Project description:We performed RNA-seq to analyze gene expression in human PASMCs (Pulmonary arterial smooth muscle cells) isolated from subjects without disease and from subjects with IPAH (idiopathic pulmonary hypertension)

2020-07-15 | GSE144274 | GEO

TiO2-induced gene expression profiles in rat lung: a subacute inhalation study.

Project description:In this work we study the pulmonary toxicological properties of titanium dioxide using conventional and molecular toxicological approaches. For this, we exposed Fischer 344 rats by nose-only inhalation 6 hours/day, 5 days/week for 4 weeks to a nanoaerosol of TiO2 (10 mg/m3). Lung samples have been collected up to 180 days after the end of exposure. Biochemical and cytological analyses of the broncho-alveolar lavage fluid (BALF) were performed. In addition, transcriptomic and proteomic approaches were realised in the lung and BALF respectively.

2019-01-17 | GSE99997 | GEO

Azithromycin effects on lung microbiome in COPD patient

Project description:Azithromycin (AZM) reduces pulmonary inflammation and exacerbations in chronic obstructive pulmonary disease patients with emphysema. The antimicrobial effects of AZM on the lung microbiome are not known and may contribute to its beneficial effects. Methods. Twenty smokers with emphysema were randomized to receive AZM 250 mg or placebo daily for 8 weeks. Bronchoalveolar lavage (BAL) was performed at baseline and after treatment. Measurements included: rDNA gene quantity and sequence. Results. Compared with placebo, AZM did not alter bacterial burden but reduced α-diversity, decreasing 11 low abundance taxa, none of which are classical pulmonary pathogens. Conclusions. AZM treatment the lung microbiome

2016-07-19 | GSE74396 | GEO

RNA-sequencing of primary human PASMCs and CFs for estimating GPCR expression

Project description:RNA-seq was performed on primary human pulmonary arterial smooth muscle cells (PASMCs) and cardiac fibroblasts (CFs)

2019-10-28 | GSE125049 | GEO

Comprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice

Project description:Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compared to conventional cigarettes. We investigated physiological and histological endpoints in parallel with transcriptomics, lipidomics, and proteomics profiles in mice exposed to a reference cigarette (3R4F) smoke or a pMRTP aerosol for up to 7 months. We also included a cessation group and a switching-to-pMRTP group (after 2 months of 3R4F exposure) in addition to the control (fresh air-exposed) group, to understand the potential risk reduction of switching to pMRTP compared with continuous 3R4F exposure and cessation. </p> The dataset shared here describes the lipidomics analyses performed on lung, liver, and plasma of these mice at multiple time points. Lipids were characterized using, in addition to (untargeted) shotgun lipidomics, a set of targeted methods to specifically characterize sphingolipids, ceramides, triglycerides, eicosanoids, and gangliosides.

2015-11-19 | MTBLS143 | MetaboLights

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data