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IPac-02 trial

ABSTRACT: Interventions: mFOLFOX6 + bevacizumab + IP PTX therapy:1 course for 14 days intraperitoneal paclitaxel on days 1 and 8, Intravenous infusion of bevasizumab (Bmab), levofolinate (l-LV), oxaliplatin (L-OHP), followed by bolus of fluorouracil (5-FU) on day 1. CAPOX + bevacizumab + IP PTX therapy:1 course for 21days intraperitoneal paclitaxel on days 1, 8 and 15, Intravenous infusion of bevasizumab (Bmab) and oxaliplatin (L-OHP) on day 1, oral Capecitabine on days 1-14. Primary outcome(s): Response rate Study Design: single arm study, open(masking not used), uncontrolled control, single assignment, treatment purpose

DISEASE(S): Colorectal Cancer,Colorectal Cancer With Peritoneal Metastases

PROVIDER: 2740711 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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