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METIMMOX-2: Metastatic pMMR/MSS Colorectal Cancer - Shaping Anti-Tumor Immunity by Oxaliplatin

ABSTRACT: Hypothesis: Patients with metastatic colorectal cancer with DNA mismatch repair-proficient (pMMR) function / microsatellite-stable (MSS) phenotype harbor a non-immunogenic disease that can be transformed into an immunogenic condition by short-course oxaliplatin-based therapy, and may achieve durable disease control or even tumor eradication by the addition of immune checkpoint blockade therapy to the standard-of-care oxaliplatin-based treatment.

DISEASE(S): Adenocarcinoma,Colorectal Adenocarcinoma,Cystadenocarcinoma,Carcinoma, Signet Ring Cell,Mucinous Adenocarcinoma,Signet Ring Cell Adenocarcinoma,Adenocarcinoma, Mucinous

PROVIDER: 2745450 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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