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A Phase 1/2a Study of IMM-1-104 in Participants With Previously Treated, RAS-Mutant, Advanced or Metastatic Solid Tumors

ABSTRACT: This is an open-label, dose-exploration and expansion study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of IMM-1-104 when administered as monotherapy in participants with RAS-mutated advanced or metastatic solid tumors. The dose exploration will identify the candidate recommended Phase 2 dose (RP2D) of IMM-1-104 to further explore the anti-tumor activity of IMM-1-104 as monotherapy in 4 Phase 2a tumor-specific cohorts.

DISEASE(S): Adenocarcinoma,Colorectal Cancer (crc),Pancreatic Adenocarcinoma,Melanoma,Advanced Cancer,Advanced Solid Tumor (phase 1),Non-small Cell Lung Cancer (nsclc),Malignant Melanoma (cutaneous)

PROVIDER: 2751815 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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