Developing questionnaires in Indian context for assessing deitary habits and level of physical activity in colon and rectal cancer patient
Ontology highlight
ABSTRACT:
DISEASE(S): Disease Of Digestive System, Unspecified
PROVIDER: 57169 | ecrin-mdr-crc |
REPOSITORIES: ECRIN MDR
Similar Datasets
Project description:Objectivesto determine the concurrent validity of a physical activity diary for measuring physical activity level and total energy expenditure in hospitalized stroke patients.MethodSixteen stroke patients kept coded activity diaries and wore SenseWear Pro2 multi-sensor activity monitors during daytime hours for one day. A researcher observed the patients and completed a diary. Data from the patients' diaries were compared with observed and measured data to determine total activity (METs*minutes), activity level and total energy expenditure.ResultsSpearman correlations between the patients' and researchers' diaries revealed a high correlation for total METs*minutes (rs?=?0.75, p<0.01) for sedentary (rs?=?0.74,p<0.01) and moderate activities (rs?=?0.71,p<0.01) and a very high correlation (rs?=?0.92, p<0.01) for the total energy expenditure. Comparisons between the patients' diaries and activity monitor data revealed a low correlation (rs 0.29) for total METs*minutes and energy expenditure.ConclusionCoded self-monitoring activity diaries appear feasible as a low-tech alternative to labor-intensive observational diaries for determining sedentary, moderate, and total physical activity and for quantifying energy expenditure in hospitalized stroke patients. Given the poor correlation with objective measurements of physical activity, however, further research is needed to validate its use against a gold-standard measure of physical activity intensity and energy expenditure.
| S-EPMC4048313 | biostudies-literature
Project description:Interventions: The intervention arm is named HoPS, an acronym of Home-based Physical Activity for Survivors.
HoPS intervention programme aims to improve physical activity level among cancer survivors, in particular breast and colorectal cancer by employing Social Cognitive Theory (SCT) in the development of the programme. It combines of psychoeducation and social media approach to behavioural intervention. Participants of the HoPS will be provided with a non-tailored printed material and gradual tapering down of face-to-face group meetings to improve knowledge and skills of physical activity. While WhatsApp is used as a structured direct remote feedback strategy to allow for supervised home-based physical activity.
1. Face-to-face group meetings
There will be 2 meet up sessions for all participants in the HoPS group. The sessions provide a standardized lectures deliver by the researcher using power point slides. The first session of lecture (1-hour duration) will cover the areas of a brief introduction of HoPS programme, physical activity knowledge and goal setting. The second session of lecture (15-minutes duration) will cover for barriers to physical activity and following that a sharing session (15-minutes duration) by a role model (a cancer survivor) to share her experience in engaging in physical activity. In each of the sessions, after the lectures, an exercise session will be conducted by a certified exercise instructor with at least 3 years experienced in coaching for exercise. The duration of this exercise session will be 2 hours and the focus is train the participants on how to perform a proper and correct exercise for cancer survivors. This will involved aerobic exercises and resistance exercis
Primary outcome(s): Total MET-minutes/week using validated IPAQ [Baseline, at 8-week (immediately after intervention) and at 16-week post intervention]
Study Design: Purpose: Educational / counselling / training; Allocation: Randomised controlled trial; Masking: Blinded (masking used);Assignment: Parallel;Type of endpoint: Efficacy
| 2470261 | ecrin-mdr-crc
Project description:Gene expression profoling of developping endosperm at 3 and 6 days after flowering (DAH): Nipponbare vs NIL(TGW6) We used two rice varieties, NIL(TGW6) and Nipponbare.NIL(TGW6) is a nearly isogenic line containing the thousand grain weight qTGW6. For samples used three stages: 3 and 6 DAH endosperm in both Nipponbare and NIL(TGW6). Two dye swapped experiments were performed.
2013-02-12 | E-GEOD-44223 | biostudies-arrayexpress
Project description:Gene expression profoling of developping endosperm at 3 and 6 days after flowering (DAH): Nipponbare vs NIL(TGW6)
2013-02-12 | GSE44223 | GEO
Project description:BackgroundPhysical activity data provides important information on disease onset, progression, and treatment outcomes. Although analyzing physical activity data in conjunction with other clinical and microbiological data will lead to new insights crucial for improving human health, it has been hampered partly because of the large variations in the way the data are collected and presented.ObjectiveThe aim of this study was to develop a Physical Activity Ontology (PACO) to support structuring and standardizing heterogeneous descriptions of physical activities.MethodsWe prepared a corpus of 1140 unique sentences collected from various physical activity questionnaires and scales as well as existing standardized terminologies and ontologies. We extracted concepts relevant to physical activity from the corpus using a natural language processing toolkit called Multipurpose Text Processing Tool. The target concepts were formalized into an ontology using Protégé (version 4). Evaluation of PACO was performed to ensure logical and structural consistency as well as adherence to the best practice principles of building an ontology. A use case application of PACO was demonstrated by structuring and standardizing 36 exercise habit statements and then automatically classifying them to a defined class of either sufficiently active or insufficiently active using FaCT++, an ontology reasoner available in Protégé.ResultsPACO was constructed using 268 unique concepts extracted from the questionnaires and assessment scales. PACO contains 225 classes including 9 defined classes, 20 object properties, 1 data property, and 23 instances (excluding 36 exercise statements). The maximum depth of classes is 4, and the maximum number of siblings is 38. The evaluations with ontology auditing tools confirmed that PACO is structurally and logically consistent and satisfies the majority of the best practice rules of ontology authoring. We showed in a small sample of 36 exercise habit statements that we could formally represent them using PACO concepts and object properties. The formal representation was used to infer a patient activity status category of sufficiently active or insufficiently active using the FaCT++ reasoner.ConclusionsAs a first step toward standardizing and structuring heterogeneous descriptions of physical activities for integrative data analyses, PACO was constructed based on the concepts collected from physical activity questionnaires and assessment scales. PACO was evaluated to be structurally consistent and compliant to ontology authoring principles. PACO was also demonstrated to be potentially useful in standardizing heterogeneous physical activity descriptions and classifying them into clinically meaningful categories that reflect adequacy of exercise.
| S-EPMC6658272 | biostudies-literature
Project description:Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Primary outcome(s): 1.To assess the functional outcomes of patients after sphincter preserving surgery
2.To assess the quality of life of patients after sphincter preserving surgery
3.To find out the correlation in selected demographic variables with the functional outcomes and quality of lifeTimepoint: Single time point after study enrollment
| 2584109 | ecrin-mdr-crc
Project description:BACKGROUND:Physical activity (PA) in adolescence is crucial for lifelong healthy lifestyle, and attention is needed to adolescents at health risk due to insufficient PA. This study investigates the composition of weekly PA in adolescents by PA level and provides a rationale for change in their lifestyles. METHODS:The research was conducted at 66 schools in Poland between 2009 and 2016, among 949 girls and 650 boys aged 15-18?years. We used pedometers to monitor weekly PA with data assessed using the Indares web app. The participants were split into three groups by mean daily step count (lower, < 9000; middle, 9000-12,999; and higher, ? 13,000 steps/day), as a reliable and non-expensive indicator of PA. RESULTS:We did not observe statistically significant differences in composition of 7-day PA between participants with varying levels of PA, regardless of their gender (F(12,9558)?=?0.60; p?=?0.841; ?p2?>?0.000). The smallest differences in daily step counts by PA level were found on Mondays and the biggest on Fridays and Saturdays, in boys and girls; the differences between average school and average weekend days were most pronounced in less active girls (1677 steps/day) and boys (1886 steps/day). During the school week, the highest proportion of less active girls met the 11,000 steps/day recommendation on Fridays (21.9%), statistically significantly less than on other school days (p?<?0.001). Similarly, less active boys (22.2%) had significantly less activity on Fridays than on other school days, except for Mondays (p?=?0.143) Analogous pattern was apparent also in more active adolescents. CONCLUSIONS:Less active adolescents have comparable composition of weekly PA to the more active ones but they can hardly meet the generally accepted PA recommendations. Better understanding of weekly PA composition and rates of meeting PA recommendations by day of the week can lead to more efficient interventions improving lifestyles. The recommendation of 9000 steps/day most days of the week, thus, appears appropriate for less active adolescents, as a motivating achievable goal.
| S-EPMC7183676 | biostudies-literature
Project description:Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Primary outcome(s): To understand the clinical profile (e.g. Baseline demographics, Clinical presentations, co-morbid conditions, Performance
status etc.) of Metastatic Colorectal cancer (mCRC) patients undergoing treatment
ï?· To understand the tumour characteristics (tumour location, Site of metastasis, Number of metastatic sites, Molecular profile [KRAS including KRAS G12C, BRAF, MSI/MSS, HER2 etc) of Metastatic Colorectal cancer (mCRC) patients undergoing
treatment.
ï?· To understand the current treatment pattern of Metastatic Colorectal cancer (mCRC) patients
ï?· To understand Treatment outcomes in Metastatic Colorectal cancer (mCRC) patients undergoing treatmentTimepoint: Baseline(Day 0), Follow up (3-6 months), follw up (12-18 months)
| 2757018 | ecrin-mdr-crc
Project description:Intervention1: NIL: NIL
Primary outcome(s): Clinical profile & tumor characteristics of mCRC patients
Usage pattern of targeted therapies (bevacizumab, cetuximab, and panitumumab) in mCRC patients
Overall Response Rate (ORR)
Clinical Benefit Rate (CBR)
Progression Free Survival (PFS)
Duration of Response (DoR)
Overall Survival (OS)
Adverse drug reactions associated with targeted therapyTimepoint: Baseline and follow up as per routine clinical practice
| 96797 | ecrin-mdr-crc
Project description:BACKGROUND:Physical activity (PA) can support cancer patients during medical treatment by reducing side-effects and increasing quality of life. However, PA levels mostly decline after diagnosis. Which factors can explain if patients are able to remain or even increase their PA level? Self-efficacy is an important cognitive factor that has been linked to cancer patients' PA across many studies. In contrast, affective factors such as PA enjoyment have rarely been examined. We compare the influence of self-efficacy and PA enjoyment on cancer patients' PA levels after completion of an exercise or stress-management intervention. METHODS:Outpatient cancer patients [N = 72; 54% female; M = 56 years, SD = 12.34; most with breast or colon cancer (34%, 15%)] were enrolled in the MOTIVACTION study, a 4-week intervention (1 h counseling followed by weekly phone calls), with pre-test (T1), post-test (T2), and a 10-week follow-up (T3). Participants were randomized to either an exercise intervention (emphasizing self-regulatory strategies for behavior change) or to a stress management intervention (coping and relaxation techniques). Sixty-seven patients remained in the study and completed the SQUASH assessment of PA, a measure of maintenance self-efficacy (7 items, Cronbach's ? = 0.88) and PA enjoyment (2 items, Cronbach's ? = 0.89). Regression analyses were calculated with PA level (at T2 and T3) as dependent variable and relative weight analyses were conducted. The study was registered at clinicalTrials.gov (unique identifier:NCT01576107; URL: https://clinicaltrials.gov/ct2/show/NCT01576107?term=motivaction&rank=1). RESULTS:Baseline self-efficacy and change in PA enjoyment significantly predicted cancer patients' PA level at T2 adjusting for baseline PA and type of intervention. Relative weight (RW) analysis revealed that PA enjoyment (baseline and change together) explained 34.3% of the dependent variable, self-efficacy (baseline and change) explained 38.4%. At follow-up, self-efficacy was still a significant predictor of PA (RW = 74.6%), whereas PA enjoyment was no longer a relevant factor (RW = 5.2%). CONCLUSION:The affective factor PA enjoyment was equally important as self-efficacy for predicting cancer patient' PA level directly after completion of the intervention. Reasons for the reduced relevance at follow-up and a broader range of affective factors should be analyzed in future studies on cancer patients' PA level.
| S-EPMC4914598 | biostudies-literature