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A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

ABSTRACT: To evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors * To evaluate the safety and tolerability of naporafenib administered with trametinib in patients with RAS Q61X solid tumors * To characterize the pharmacokinetic (PK) profile of naporafenib and trametinib when administered to patients with RAS Q61X solid tumors

DISEASE(S): Thyroid Cancer,Melanoma,Non-small Cell Lung Cancer,Colorectal Cancer,Advanced Or Metastatic Solid Tumors,Pancreatic Cancer

PROVIDER: 63675 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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