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Fluid Challenge and Plasma Volume, During Surgery

ABSTRACT: A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique. The purpose with the study is to examine the plasma expanding effect of three different fluid challenge strategies (acetated Ringers 4 ml/kg body weight, albumin 5% 4 ml/kg body weight or albumin 20% 1 ml/kg body weight), using hemoglobin as a dilution indicator.

DISEASE(S): Gynecologic Cancer,Benign Neoplasm,Colorectal Disorders,Urologic Cancer,Colorectal Cancer,Urologic Neoplasms,Neoplasms

PROVIDER: 8191 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344

Project description:In order to gain insight into the effects of aging on susceptibility to environmental toxins, we characterized the expression of xenobiotic metabolizing enzymes (XMEs) from the livers of male Brown Norway and F344 rats across the adult lifespan. To examine metabolic processes across lifespan after challenge with a xenobiotic compound, Brown Norway rats were exposed to 1.0 g/kg body weight toluene by oral gavage in corn oil (4ml/kg body weight) or corn oil alone. Keywords: age effect on toxin susceptibility

2008-07-30 | GSE11097 | GEO

Effect of beta3 adrenergic activation on liver gene expression profile in mice (C57Bl/6J) expressing hepatocyte PPARalpha or not

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2011-07-12 | E-GEOD-30576 | biostudies-arrayexpress

Mouse kidney after systemic endotoxin challenge

2011-07-12 | GSE30576 | GEO

High-protein intake eliminates the weight loss-induced improvement in insulin sensitivity

Project description:The purpose of this study was to conduct a randomized-controlled trial to evaluate the effect of a high-protein (HP) diet weight loss (WL) on changes in body composition, insulin sensitivity and skeletal muscle gene expression profile in postmenopausal women who were obese and randomized to one of three dietary intervention groups: 1) a weight maitenance group, 2) a weight loss group (normal protein intake, 0.8 g protein/kg body weight per day) and 3) a weight loss group (high protein intake, 1.2 g protein/kg body weight per day) and studies before and after they lost 10% of their body weight (WL groups) or a time-matched weight maintenacne period.

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Transcription profiling of mouse jejunum detached peyers patch from mice orally administered lactoperoxidase (LPO) to study influence of bovine LPO on the digestive tract.

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2014-03-17 | E-GEOD-55733 | biostudies-arrayexpress

gene expression of ventral prostate in rat

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2014-01-15 | E-MTAB-2181 | biostudies-arrayexpress

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