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Testing ONC201 to Prevent Colorectal Cancer

ABSTRACT: This phase I trial tests the safety, side effects, and best dose of Akt/ERK Inhibitor ONC201 (ONC201) in preventing colorectal cancer in patients with familial adenomatous polyposis (FAP) or a history of multiple polyps. ONC201 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

DISEASE(S): Colorectal Carcinoma,Multiple Adenomatous Polyps,Adenomatous Polyps,Adenomatous Polyposis Coli,Colorectal Neoplasms,Familial Adenomatous Polyposis,Colorectal Adenomatous Polyp,Polyps

PROVIDER: 860 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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