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Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Rectal Cancer


ABSTRACT: The goal of this clinical trial is to compare in newly diagnosed patients with resectable rectal cancer with lateral lymph node metastasis. This study aims to * further verify the safety and efficacy of FOLFOXIRI three-drug regimen * Using multiple omics techniques to identify and confirm specific molecular markers Participants will be treated with FOLFOXIRI three-drug combination regimen. Researchers will compare another group treated with conventional preoperative chemoradiotherapy to see if the experimental group is superior to the control group in terms of 3-year disease free survival, local recurrence rate, lateral lymph node positivity rate, and 5-year overall survival rate.

DISEASE(S): Neoplasm Metastasis,Rectal Neoplasms,Gastrointestinal Neoplasms,Oxaliplatin,Rectal Diseases,Lymph Node Metastasis,Lymphatic Metastasis,Cancer Of Rectum And Anus,Intestinal Neoplasms,Digestive System Neoplasms,Neoplasms

PROVIDER: 92794 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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