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Gencord Data Access Committee

ABSTRACT: Data Access Committee EGAC00001000105

PROVIDER: EGAC00001000105 | EGA |

REPOSITORIES: EGA

ACCESS DATA

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Publications

Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts.

Borel Christelle C Deutsch Samuel S Letourneau Audrey A Migliavacca Eugenia E Montgomery Stephen B SB Dimas Antigone S AS Vejnar Charles E CE Attar Homa H Gagnebin Maryline M Gehrig Corinne C Falconnet Emilie E Dupré Yann Y Dermitzakis Emmanouil T ET Antonarakis Stylianos E SE

Genome research 20101208 1

MicroRNAs (miRNAs) are regulatory noncoding RNAs that affect the production of a significant fraction of human mRNAs via post-transcriptional regulation. Interindividual variation of the miRNA expression levels is likely to influence the expression of miRNA target genes and may therefore contribute to phenotypic differences in humans, including susceptibility to common disorders. The extent to which miRNA levels are genetically controlled is largely unknown. In this report, we assayed the expres ...[more]

PMID: 21147911

Publication: 1/3

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