Project description:The Genetic Association Information Network (GAIN) Data Access Committee was established in June 2007 to provide prompt and fair access to data from six genome-wide association studies through the database of Genotypes and Phenotypes (dbGaP). Of 945 project requests received through 2011, 749 (79%) have been approved; median receipt-to-approval time decreased from 14 days in 2007 to 8 days in 2011. Over half (54%) of the proposed research uses were for GAIN-specific phenotypes; other uses were for method development (26%) and adding controls to other studies (17%). Eight data-management incidents, defined as compromises of any of the data-use conditions, occurred among nine approved users; most were procedural violations, and none violated participant confidentiality. Over 5 years of experience with GAIN data access has demonstrated substantial use of GAIN data by investigators from academic, nonprofit, and for-profit institutions with relatively few and contained policy violations. The availability of GAIN data has allowed for advances in both the understanding of the genetic underpinnings of mental-health disorders, diabetes, and psoriasis and the development and refinement of statistical methods for identifying genetic and environmental factors related to complex common diseases.

| S-EPMC3617375 | biostudies-literature

TNBC (COH_TNBC_RNAseq) - Data Access Committee at The Jackson laboratory

Project description:Data Access Committee EGAC00001002518

| EGAC00001002518 | EGA

TNBC (COH_WGS) - Data Access Committee at The Jackson laboratory

Project description:Data Access Committee EGAC00001002574

| EGAC00001002574 | EGA

TNBC (UW_OvCa_RNASeq) - Data Access Committee at The Jackson laboratory

Project description:Data Access Committee EGAC00001002524

| EGAC00001002524 | EGA

TNBC (UW_OvCa_WGS) - Data Access Committee at The Jackson laboratory

Project description:Data Access Committee EGAC00001002544

| EGAC00001002544 | EGA

Wellcome Trust Case Control Consortium Data Access Committee

Project description:Access to summary data and individual-level genotype data is available by application to the Wellcome Trust Case Control Consortium Data Access Committee (CDAC). Access to data will be granted to qualified investigators for appropriate use. The CDAC also controls the individual level genotype data for the 1958 British Birth Cohort samples. For further guidelines, application form and data access agreement, please follow the link below.

| EGAC00000000001 | EGA

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