Dataset Information
UHN Genomics Data Access Committee
Ontology highlight
ABSTRACT:
PROVIDER: EGAC00001000912 | EGA |
REPOSITORIES: EGA
Publications
Testing ERBB2 p.L755S kinase domain mutation as a druggable target in a patient with advanced colorectal cancer.
Cold Spring Harbor molecular case studies 20160901 5
Recent advances in molecular profiling technologies allow genetic driver events in individual tumors to be identified. The hypothesis behind this ongoing molecular profiling effort is that improvement in patients' clinical outcomes will be achieved by inhibiting these discovered genetic driver events with matched targeted drugs. This hypothesis is currently being tested in oncology clinics with variable early results. Herein, we present our experience with a case of advanced colorectal cancer (C ...[more]