Dataset Information
Data Access Commitee for gastric cancer ascites
Ontology highlight
ABSTRACT:
PROVIDER: EGAC00001001026 | EGA |
REPOSITORIES: EGA
Publications
Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response.
Gut 20190606 1
<h4>Objective</h4>Peritoneal carcinomatosis (PC) occurs frequently in patients with gastric adenocarcinoma (GAC) and confers a poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC's development/progression remain largely unknown. We characterised exome/transcriptome/immune landscapes of PC cells from patients with GAC aiming to identify novel therapeutic targets.<h4>Design</h4>We performed whole-exome sequencing (WES) and whole transcriptome sequenc ...[more]