Project description:In this study, we investigated somatic mutations in T cells in patients with various hematological disorders. To analyze immune cell phenotypes with somatic mutations, we performed scRNA+TCRab sequencing from 9 patients with chronic GVHD and clonal expansions of CD4+ or CD8+ T cells based on T cell receptor sequencing. CD45+ PBMCs (lymphocytes and monocytes) were sorted with BD Influx cell sorter and subjected to sequencing with Chromium VDJ and Gene Expression platform (v1.1, 10X Genomics). Sequencing was performed with Novaseq 6000 (Illumina). The immune cell phenotypes were compared to healthy controls processed in the same laboratory (accession number E-MTAB-11170). Due to data privacy concerns, the raw sequencing data is in the European Genome-Phenome Archive (EGA) under accession code [xxxx] and can be requested through the EGA Data Access Committee.

2024-04-10 | E-MTAB-13419 | biostudies-arrayexpress

Imperial College London - Beta Cell Genome Regulation Lab

Project description:Data Access Committee EGAC00001000853

| EGAC00001000853 | EGA

UCSF Bivona lab.

Project description:Data Access Committee EGAC00001000711

| EGAC00001000711 | EGA

Schumacher Lab DAC

Project description:Data Access Committee EGAC00001000975

| EGAC00001000975 | EGA

Sethupathy Lab DAC

Project description:Data Access Committee EGAC00001001454

| EGAC00001001454 | EGA

modENCODE_White Lab: genome-wide ChIP-chip data

Project description:This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains ChIP-chip data on Affymetrix Drosophila Tiling 2.0R arrays for multiple transcription factor antibodies at various time-points of Drosophila development. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf

2010-11-11 | GSE25259 | GEO

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