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Uganda Medical Informatics Centre (UMIC)

ABSTRACT: Data Access Committee EGAC00001001495

PROVIDER: EGAC00001001495 | EGA |

REPOSITORIES: EGA

ACCESS DATA

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Publications

The African Genome Variation Project shapes medical genetics in Africa.

Gurdasani Deepti D Carstensen Tommy T Tekola-Ayele Fasil F Pagani Luca L Tachmazidou Ioanna I Hatzikotoulas Konstantinos K Karthikeyan Savita S Iles Louise L Pollard Martin O MO Choudhury Ananyo A Ritchie Graham R S GR Xue Yali Y Asimit Jennifer J Nsubuga Rebecca N RN Young Elizabeth H EH Pomilla Cristina C Kivinen Katja K Rockett Kirk K Kamali Anatoli A Doumatey Ayo P AP Asiki Gershim G Seeley Janet J Sisay-Joof Fatoumatta F Jallow Muminatou M Tollman Stephen S Mekonnen Ephrem E Ekong Rosemary R Oljira Tamiru T Bradman Neil N Bojang Kalifa K Ramsay Michele M Adeyemo Adebowale A Bekele Endashaw E Motala Ayesha A Norris Shane A SA Pirie Fraser F Kaleebu Pontiano P Kwiatkowski Dominic D Tyler-Smith Chris C Rotimi Charles C Zeggini Eleftheria E Sandhu Manjinder S MS

Nature 20141203 7534

Given the importance of Africa to studies of human origins and disease susceptibility, detailed characterization of African genetic diversity is needed. The African Genome Variation Project provides a resource with which to design, implement and interpret genomic studies in sub-Saharan Africa and worldwide. The African Genome Variation Project represents dense genotypes from 1,481 individuals and whole-genome sequences from 320 individuals across sub-Saharan Africa. Using this resource, we find ...[more]

PMID: 25470054

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