Project description:Purpose: ATAC-seq was performed on preterm lambs that were ventilated by invasive mechanical ventilation or noninvasive respiratory support utilizing a mask and compared to gestation-age-matched preterm lambs that were not ventilated and naturally delivered term lambs. Methods: Lung chromatin access profiles were generated for: 1) Unventilated preterm lamb, 2) preterm lambs delivered at gd131 and intubated and mechanically ventilated for 3 days, 3) preterm lambs delivered at gd131 and not intubated and resuscitated by placing a face mask over the nose and mouth and controlling O2 delivery via a computer-controlled electronic blower device, 4) unventilated naturally delivered full-term lambs. Results: Using an optimized data analysis workflow, we mapped between 76 and 96 million sequence reads per sample to the sheep genome Conclusions: Our study represents the first detailed analysis of ventilated preterm lung chromatin access, with biologic replicates, generated by ATAC-seq

2021-06-30 | GSE163807 | GEO

GLASS-NL DNA-methylation Data Access Committee

Project description:Data Access Committee EGAC00001003478

| EGAC00001003478 | EGA

ESCC DNA methylation biomarkers data access committee

Project description:Data Access Committee EGAC00001000991

| EGAC00001000991 | EGA

NOPHO-ALL DNA Methylation Data Access Committee

Project description:Data Access Committee EGAC01000000022

| EGAC01000000022 | EGA

RNA-seq access dataset for epigenomics landscape of colorectal cancer

Project description:RNA-seq access dataset for epigenomics landscape of colorectal cancer