Dataset Information

UC

ABSTRACT: WTCCC2 project Ulcerative Colitis (UC) samples

PROVIDER: EGAD00000000025 | EGA |

REPOSITORIES: EGA

ACCESS DATA

Publications

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

Barrett Jeffrey C JC Lee James C JC Lees Charles W CW Prescott Natalie J NJ Anderson Carl A CA Phillips Anne A Wesley Emma E Parnell Kirstie K Zhang Hu H Drummond Hazel H Nimmo Elaine R ER Massey Dunecan D Blaszczyk Kasia K Elliott Timothy T Cotterill Lynn L Dallal Helen H Lobo Alan J AJ Mowat Craig C Sanderson Jeremy D JD Jewell Derek P DP Newman William G WG Edwards Cathryn C Ahmad Tariq T Mansfield John C JC Satsangi Jack J Parkes Miles M Mathew Christopher G CG Donnelly Peter P Peltonen Leena L Blackwell Jenefer M JM Bramon Elvira E Brown Matthew A MA Casas Juan P JP Corvin Aiden A Craddock Nicholas N Deloukas Panos P Duncanson Audrey A Jankowski Janusz J Markus Hugh S HS Mathew Christopher G CG McCarthy Mark I MI Palmer Colin N A CN Plomin Robert R Rautanen Anna A Sawcer Stephen J SJ Samani Nilesh N Trembath Richard C RC Viswanathan Anath C AC Wood Nicholas N Spencer Chris C A CC Barrett Jeffrey C JC Bellenguez Céline C Davison Daniel D Freeman Colin C Strange Amy A Donnelly Peter P Langford Cordelia C Hunt Sarah E SE Edkins Sarah S Gwilliam Rhian R Blackburn Hannah H Bumpstead Suzannah J SJ Dronov Serge S Gillman Matthew M Gray Emma E Hammond Naomi N Jayakumar Alagurevathi A McCann Owen T OT Liddle Jennifer J Perez Marc L ML Potter Simon C SC Ravindrarajah Radhi R Ricketts Michelle M Waller Matthew M Weston Paul P Widaa Sara S Whittaker Pamela P Deloukas Panos P Peltonen Leena L Mathew Christopher G CG Blackwell Jenefer M JM Brown Matthew A MA Corvin Aiden A McCarthy Mark I MI Spencer Chris C A CC Attwood Antony P AP Stephens Jonathan J Sambrook Jennifer J Ouwehand Willem H WH McArdle Wendy L WL Ring Susan M SM Strachan David P DP

Nature genetics 20091115 12

Ulcerative colitis is a common form of inflammatory bowel disease with a complex etiology. As part of the Wellcome Trust Case Control Consortium 2, we performed a genome-wide association scan for ulcerative colitis in 2,361 cases and 5,417 controls. Loci showing evidence of association at P < 1 x 10(-5) were followed up by genotyping in an independent set of 2,321 cases and 4,818 controls. We find genome-wide significant evidence of association at three new loci, each containing at least one bio ...[more]

PMID: 19915572

Dataset Information

UC

Publications

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Similar Datasets

WTCCC2 case-control study for Ulcerative Colitis
| EGAS00000000084 | EGA

Transcription profiling of human ulcerative colitis colonic mucosa to define an ulcerative colitis preinflammatory state
2008-06-20 | E-GEOD-9452 | biostudies-arrayexpress

Genome-wide analysis of Crohn's disease and ulcerative colitis biopsy samples.
2013-09-23 | GSE36807 | GEO

Short Noncoding RNAs as predictive biomarkers for the development from Inflammatory Bowel Disease Unclassified to Crohn’s Disease or Ulcerative Colitis
2024-03-04 | GSE228622 | GEO

Genome-wide analysis of Crohn's disease and ulcerative colitis biopsy samples.
2013-09-23 | E-GEOD-36807 | biostudies-arrayexpress

MicroRNA expression in human colon: Crohn's disease versus ulcerative colitis
2014-12-31 | GSE53867 | GEO

Genentech IBD Fecal Proteomics
2022-04-11 | MSV000089237 | MassIVE

Gene expression profiling of sigmoid colonic tissue form patients with ulcerative colitis and healthy controls
2024-07-01 | GSE206171 | GEO

Inflammatory transcriptomic signatures and cell type compositions in inflamed and non-inflamed colonic mucosa of ulcerative colitis
2024-03-19 | GSE243625 | GEO

Transcription profiling of human ulcerative colitis samples to develop a molecular marker
2008-06-12 | E-GEOD-3629 | biostudies-arrayexpress