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EGAD00000000026

ABSTRACT: Randomly-selected, unrelated individuals

PROVIDER: EGAD00000000026 | EGA |

REPOSITORIES: EGA

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Publications

Metabonomic, transcriptomic, and genomic variation of a population cohort.

Inouye Michael M Kettunen Johannes J Soininen Pasi P Silander Kaisa K Ripatti Samuli S Kumpula Linda S LS Hämäläinen Eija E Jousilahti Pekka P Kangas Antti J AJ Männistö Satu S Savolainen Markku J MJ Jula Antti A Leiviskä Jaana J Palotie Aarno A Salomaa Veikko V Perola Markus M Ala-Korpela Mika M Peltonen Leena L

Molecular systems biology 20101201

Comprehensive characterization of human tissues promises novel insights into the biological architecture of human diseases and traits. We assessed metabonomic, transcriptomic, and genomic variation for a large population-based cohort from the capital region of Finland. Network analyses identified a set of highly correlated genes, the lipid-leukocyte (LL) module, as having a prominent role in over 80 serum metabolites (of 134 measures quantified), including lipoprotein subclasses, lipids, and ami ...[more]

PMID: 21179014

Publication: 1/2

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