Genomics

Dataset Information

0

MELARISK_SNP_MITF_geno

ABSTRACT: Genotypes at MITF E318K variant

PROVIDER: EGAD00000000122 | EGA |

REPOSITORIES: EGA

Json Xml
altmetric image

Publications

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.

Bertolotto Corine C   Lesueur Fabienne F   Giuliano Sandy S   Strub Thomas T   de Lichy Mahaut M   Bille Karine K   Dessen Philippe P   d'Hayer Benoit B   Mohamdi Hamida H   Remenieras Audrey A   Maubec Eve E   de la Fouchardière Arnaud A   Molinié Vincent V   Vabres Pierre P   Dalle Stéphane S   Poulalhon Nicolas N   Martin-Denavit Tanguy T   Thomas Luc L   Andry-Benzaquen Pascale P   Dupin Nicolas N   Boitier Françoise F   Rossi Annick A   Perrot Jean-Luc JL   Labeille Bruno B   Robert Caroline C   Escudier Bernard B   Caron Olivier O   Brugières Laurence L   Saule Simon S   Gardie Betty B   Gad Sophie S   Richard Stéphane S   Couturier Jérôme J   Teh Bin Tean BT   Ghiorzo Paola P   Pastorino Lorenza L   Puig Susana S   Badenas Celia C   Olsson Hakan H   Ingvar Christian C   Rouleau Etienne E   Lidereau Rosette R   Bahadoran Philippe P   Vielh Philippe P   Corda Eve E   Blanché Hélène H   Zelenika Diana D   Galan Pilar P   Aubin François F   Bachollet Bertrand B   Becuwe Céline C   Berthet Pascaline P   Bignon Yves Jean YJ   Bonadona Valérie V   Bonafe Jean-Louis JL   Bonnet-Dupeyron Marie-Noëlle MN   Cambazard Fréderic F   Chevrant-Breton Jacqueline J   Coupier Isabelle I   Dalac Sophie S   Demange Liliane L   d'Incan Michel M   Dugast Catherine C   Faivre Laurence L   Vincent-Fétita Lynda L   Gauthier-Villars Marion M   Gilbert Brigitte B   Grange Florent F   Grob Jean-Jacques JJ   Humbert Philippe P   Janin Nicolas N   Joly Pascal P   Kerob Delphine D   Lasset Christine C   Leroux Dominique D   Levang Julien J   Limacher Jean-Marc JM   Livideanu Cristina C   Longy Michel M   Lortholary Alain A   Stoppa-Lyonnet Dominique D   Mansard Sandrine S   Mansuy Ludovic L   Marrou Karine K   Matéus Christine C   Maugard Christine C   Meyer Nicolas N   Nogues Catherine C   Souteyrand Pierre P   Venat-Bouvet Laurence L   Zattara Hélène H   Chaudru Valérie V   Lenoir Gilbert M GM   Lathrop Mark M   Davidson Irwin I   Avril Marie-Françoise MF   Demenais Florence F   Ballotti Robert R   Bressac-de Paillerets Brigitte B  

Nature 20111019 7375

So far, no common environmental and/or phenotypic factor has been associated with melanoma and renal cell carcinoma (RCC). The known risk factors for melanoma include sun exposure, pigmentation and nevus phenotypes; risk factors associated with RCC include smoking, obesity and hypertension. A recent study of coexisting melanoma and RCC in the same patients supports a genetic predisposition underlying the association between these two cancers. The microphthalmia-associated transcription factor (M  ...[more]

Similar Datasets

Genomics CTCF ChIP-seq of human acute leukemias
2023-08-31 | E-MTAB-13117 | biostudies-arrayexpress
Genomics H3K27ac ChIP-seq of human acute leukemias and healthy donors
2023-08-31 | E-MTAB-13119 | biostudies-arrayexpress
Transcriptomics The effect of anti-HER2/CD3 TDB on transcription in human CD8 T cells (bulk)
2019-09-06 | E-MTAB-8211 | biostudies-arrayexpress
Transcriptomics The effect of anti-HER2/CD3 TDB on transcription in human PBMCs (single-cell)
2019-09-06 | E-MTAB-8212 | biostudies-arrayexpress
Transcriptomics Hi-C of human acute leukemias and healthy donors
2023-08-31 | E-MTAB-13122 | biostudies-arrayexpress
Genomics CGH: NAM parent lines vs. Wm82-ISU-01
2014-03-30 | GSE56351 | GEO
Genomics CGH: Transgenic soybeans and controls
2015-09-30 | GSE73596 | GEO
Transcriptomics Single-cell RNA sequencing of erythroid and megakaryocytic acute myeloid leukemia patient cells
2022-12-05 | E-MTAB-12607 | biostudies-arrayexpress
Transcriptomics Chromatin accessibility (ATAC-seq) of human acute leukemias and healthy donors
2023-08-31 | E-MTAB-13118 | biostudies-arrayexpress
Transcriptomics Single-cell RNA sequencing of colorectal cancer
2022-09-16 | E-MTAB-9934 | biostudies-arrayexpress