Dataset Information
Ena-DATASET-CbG-09-08-2013-11:02:48:049-8 - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001000643 | EGA |
REPOSITORIES: EGA
Publications
seqCNA: an R package for DNA copy number analysis in cancer using high-throughput sequencing.
BMC genomics 20140305
<h4>Background</h4>Deviations in the amount of genomic content that arise during tumorigenesis, called copy number alterations, are structural rearrangements that can critically affect gene expression patterns. Additionally, copy number alteration profiles allow insight into cancer discrimination, progression and complexity. On data obtained from high-throughput sequencing, improving quality through GC bias correction and keeping false positives to a minimum help build reliable copy number alter ...[more]