Dataset Information
Ena-DATASET-MCGILL-25-11-2015-16:14:18:542-9 - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001001688 | EGA |
REPOSITORIES: EGA
Publications
Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation.
Genome biology 20151223
<h4>Background</h4>CpG methylation variation is involved in human trait formation and disease susceptibility. Analyses within populations have been biased towards CpG-dense regions through the application of targeted arrays. We generate whole-genome bisulfite sequencing data for approximately 30 adipose and blood samples from monozygotic and dizygotic twins for the characterization of non-genetic and genetic effects at single-site resolution.<h4>Results</h4>Purely invariable CpGs display a bimod ...[more]
