Ena-DATASET-DCPTCUHK-01-02-2019-02:28:02:357-70 - samples
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ABSTRACT:
PROVIDER: EGAD00001004590 | EGA |
REPOSITORIES: EGA
Publications
Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma.
Jiang Peiyong P Sun Kun K Tong Yu K YK Cheng Suk Hang SH Cheng Timothy H T THT Heung Macy M S MMS Wong John J Wong Vincent W S VWS Chan Henry L Y HLY Chan K C Allen KCA Lo Y M Dennis YMD Chiu Rossa W K RWK
Proceedings of the National Academy of Sciences of the United States of America 20181029 46
Circulating tumor-derived cell-free DNA (ctDNA) analysis offers an attractive noninvasive means for detection and monitoring of cancers. Evidence for the presence of cancer is dependent on the ability to detect features in the peripheral circulation that are deemed as cancer-associated. We explored approaches to improve the chance of detecting the presence of cancer based on sequence information present on ctDNA molecules. We developed an approach to detect the total pool of somatic mutations. W ...[more]
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2020-07-27 | PXD014754 | Pride
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