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EGAS00001002060-sc-2019-09-24T10:04:42Z - samples

ABSTRACT: Analysis of mutational signatures caused by exposure to known mutagens in human induced pluripotent stem (iPS) cells. A reference human iPS cell-line will be exposed to 100 chemicals known or proposed to be mutagenic. Following exposure to mutagen, cells will undergo a period of recovery before sub clones are generated and sequenced. The progenitor "parental" IPS cell-line will be used to generate reference sequence data, in order to determine the mutational signatures acquired as a result of exposure to different mutagens.

PROVIDER: EGAD00001005351 | EGA |

REPOSITORIES: EGA

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