Genomics

Dataset Information

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Images - samples


ABSTRACT: Metabric breast cancer samples (Images)

PROVIDER: EGAD00010000270 | EGA |

REPOSITORIES: EGA

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Publications

Modelling the spatial heterogeneity and molecular correlates of lymphocytic infiltration in triple-negative breast cancer.

Yuan Yinyin Y  

Journal of the Royal Society, Interface 20150201 103


Lymphocytic infiltration is associated with a favourable prognosis and predicts response to chemotherapy in many cancer types, including the aggressive triple-negative breast cancer (TNBC). However, it is not well understood owing to the high levels of spatial heterogeneity within tumours, which is difficult to analyse by traditional pathological assessment. This paper describes an unbiased methodology to statistically model the spatial distribution of lymphocytes among tumour cells based on aut  ...[more]

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