Genomics

Dataset Information

0

Methylation_450K_EpiMatch - samples


ABSTRACT: BLUEPRINT EpiMatch: harnessing epigenetics for hematopoietic stem cell transplantation

PROVIDER: EGAD00010000831 | EGA |

REPOSITORIES: EGA

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Publications


<h4>Background</h4>Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for many hematological conditions. Acute graft-versus-host disease (aGVHD) is a prevalent immune-mediated complication following HSCT. Current diagnostic biomarkers that correlate with aGVHD severity, progression, and therapy response in graft recipients are insufficient. Here, we investigated whether epigenetic marks measured in peripheral blood of healthy graft donors stratify aGVHD severity in  ...[more]

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