Genomics

Dataset Information

0

Trachoma_GWAS_Scarred_Cases


ABSTRACT: Gambian specimens without trachomatous scarring

PROVIDER: EGAD00010000941 | EGA |

REPOSITORIES: EGA

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Publications


Chlamydia trachomatis causes both trachoma and sexually transmitted infections. These diseases have similar pathology and potentially similar genetic predisposing factors. We aimed to identify polymorphisms and pathways associated with pathological sequelae of ocular Chlamydia trachomatis infections in The Gambia. We report a discovery phase genome-wide association study (GWAS) of scarring trachoma (1090 cases, 1531 controls) that identified 27 SNPs with strong, but not genome-wide significant,  ...[more]

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