Genomics

Dataset Information

0

Ctgap-G-1


ABSTRACT: Illumina HumanCoreExome-12v1-1_A chip typing in a Greek adolescent population

PROVIDER: EGAD00010001005 | EGA |

REPOSITORIES: EGA

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Publications

Replication of established common genetic variants for adult BMI and childhood obesity in Greek adolescents: the TEENAGE study.

Ntalla Ioanna I   Panoutsopoulou Kalliope K   Vlachou Panagiota P   Southam Lorraine L   William Rayner Nigel N   Zeggini Eleftheria E   Dedoussis George V GV  

Annals of human genetics 20130124 3


Multiple genetic loci have been associated with body mass index (BMI) and obesity. The aim of this study was to investigate the effects of established adult BMI and childhood obesity loci in a Greek adolescent cohort. For this purpose, 34 variants were selected for investigation in 707 (55.9% females) adolescents of Greek origin aged 13.42 ± 0.88 years. Cumulative effects of variants were assessed by calculating a genetic risk score (GRS-34) for each subject. Variants at the FTO, TMEM18, FAIM2,  ...[more]

Publication: 1/2

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