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SNP_dataset_1

ABSTRACT: Tissue samples using Illumina HumanOmniExpress-FFPE-12 v1.0 BeadChip

PROVIDER: EGAD00010001179 | EGA |

REPOSITORIES: EGA

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Comparing nodal versus bony metastatic spread using tumour phylogenies.

Mangiola Stefano S Hong Matthew K H MK Cmero Marek M Kurganovs Natalie N Ryan Andrew A Costello Anthony J AJ Corcoran Niall M NM Macintyre Geoff G Hovens Christopher M CM

Scientific reports 20160922

The role of lymph node metastases in distant prostate cancer dissemination and lethality is ill defined. Patients with metastases restricted to lymph nodes have a better prognosis than those with distant metastatic spread, suggesting the possibility of distinct aetiologies. To explore this, we traced patterns of cancer dissemination using tumour phylogenies inferred from genome-wide copy-number profiling of 48 samples across 3 patients with lymph node metastatic disease and 3 patients with osseo ...[more]

PMID: 27653089

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