Genomics

Dataset Information

0

RFMix

ABSTRACT: This dataset contains the per-chromosome RFMix input and output files for the local ancestry inference of 59 Aboriginal Australian genomes as reported in Malaspinas et al., 2016. Local ancestry was inferred assuming four mixing ancestral populations represented by: Europeans (27 individuals), Asians (29 individuals), Papuans (13 individuals) and Native Australians (7 individuals from the WCD region).

PROVIDER: EGAD00010001575 | EGA |

REPOSITORIES: EGA

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Publications

A genomic history of Aboriginal Australia.

Malaspinas Anna-Sapfo AS   Westaway Michael C MC   Muller Craig C   Sousa Vitor C VC   Lao Oscar O   Alves Isabel I   Bergström Anders A   Athanasiadis Georgios G   Cheng Jade Y JY   Crawford Jacob E JE   Heupink Tim H TH   Macholdt Enrico E   Peischl Stephan S   Rasmussen Simon S   Schiffels Stephan S   Subramanian Sankar S   Wright Joanne L JL   Albrechtsen Anders A   Barbieri Chiara C   Dupanloup Isabelle I   Eriksson Anders A   Margaryan Ashot A   Moltke Ida I   Pugach Irina I   Korneliussen Thorfinn S TS   Levkivskyi Ivan P IP   Moreno-Mayar J Víctor JV   Ni Shengyu S   Racimo Fernando F   Sikora Martin M   Xue Yali Y   Aghakhanian Farhang A FA   Brucato Nicolas N   Brunak Søren S   Campos Paula F PF   Clark Warren W   Ellingvåg Sturla S   Fourmile Gudjugudju G   Gerbault Pascale P   Injie Darren D   Koki George G   Leavesley Matthew M   Logan Betty B   Lynch Aubrey A   Matisoo-Smith Elizabeth A EA   McAllister Peter J PJ   Mentzer Alexander J AJ   Metspalu Mait M   Migliano Andrea B AB   Murgha Les L   Phipps Maude E ME   Pomat William W   Reynolds Doc D   Ricaut Francois-Xavier FX   Siba Peter P   Thomas Mark G MG   Wales Thomas T   Wall Colleen Ma'run CM   Oppenheimer Stephen J SJ   Tyler-Smith Chris C   Durbin Richard R   Dortch Joe J   Manica Andrea A   Schierup Mikkel H MH   Foley Robert A RA   Lahr Marta Mirazón MM   Bowern Claire C   Wall Jeffrey D JD   Mailund Thomas T   Stoneking Mark M   Nielsen Rasmus R   Sandhu Manjinder S MS   Excoffier Laurent L   Lambert David M DM   Willerslev Eske E  

Nature 20160921 7624

The population history of Aboriginal Australians remains largely uncharacterized. Here we generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25-40 thousand years ago (kya), suggesting pre-Holocene population structure in the ancient continent of Sahul (Australia, New Guinea and Tasmania). However, all of the studied Aboriginal Australian  ...[more]

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