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Dataset Information

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Oxford University


ABSTRACT: The UK Glomerulonephritis DNA Bank, with funding from the Kidney Research UK and MRC, ascertained and assembled nuclear families through probands with glomerulonephritis as a resource for carrying out genetic studies of this disease.

PROVIDER: EGAO00000000019 | EGA |

REPOSITORIES: EGA

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Publications


Demographic and family studies support the existence of a genetic contribution to the pathogenesis of IgA nephropathy, but results from genetic association studies of candidate genes are inconsistent. To systematically survey common genetic variation in this disease, we performed a genome-wide analysis in a cohort of patients with IgA nephropathy selected from the UK Glomerulonephritis DNA Bank. We used two groups of controls: parents of affected individuals and previously genotyped, unaffected,  ...[more]

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