Other,Multiomics

Dataset Information

1K

Wellcome Trust Sanger Institute


ABSTRACT: The Wellcome Trust Sanger Institute (WTSI), Hinxton, Cambridge, UK is a not-for-profit research organisation and a world famous Genome Centre dedicated to the sequencing and functional analysis of genomes. The Sanger Institute underpins biological and medical research worldwide through large-scale analysis, focused research and collaborations. Genome sequence analysis is complemented by computational interpretation and experimental analysis of gene function in a variety of model organisms. There are designated teams for library preparation, sequencing production and data processing. The data centre for computation and data distribution has recently been extended and now has in excess of 4000 terabytes (Tb) of storage space available and a compute farm consisting of almost 5,000 CPUs.

OTHER RELATED OMICS DATASETS IN: PXD006006PRJNA127545PRJNA144907

PROVIDER: EGAO00000000020 | EGA |

REPOSITORIES: EGA

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Publications

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.

Nature 20070601 7145


There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix GeneChip 500K Mapping Array Set) undertaken in the British population, which has examined approximately 2,000 individuals for each of 7 major diseases and a shared set of approximately 3,000 controls. Case-control comparisons identified 24 independent association signals at P < 5  ...[more]

Publication: 1/57

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