BLUEPRINT
Ontology highlight
ABSTRACT:
PROVIDER: EGAO00000000072 | EGA |
REPOSITORIES: EGA
Publications
A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.
Paul Dirk S DS Jones Allison A Sellar Rob S RS Mayor Neema P NP Feber Andrew A Webster Amy P AP Afonso Neuza N Sergeant Ruhena R Szydlo Richard M RM Apperley Jane F JF Widschwendter Martin M Mackinnon Stephen S Marsh Steven G E SG Madrigal J Alejandro JA Rakyan Vardhman K VK Peggs Karl S KS Beck Stephan S
Genome medicine 20151215
<h4>Background</h4>Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for many hematological conditions. Acute graft-versus-host disease (aGVHD) is a prevalent immune-mediated complication following HSCT. Current diagnostic biomarkers that correlate with aGVHD severity, progression, and therapy response in graft recipients are insufficient. Here, we investigated whether epigenetic marks measured in peripheral blood of healthy graft donors stratify aGVHD severity in ...[more]
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Project description:This SuperSeries is composed of the SubSeries listed below.
2016-11-06 | GSE87197 | GEO
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