VUmc - CCA Genome Core
Ontology highlight
ABSTRACT:
PROVIDER: EGAO00000000238 | EGA |
REPOSITORIES: EGA
Publications
MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing.
Neerincx M M Sie D L S DL van de Wiel M A MA van Grieken N C T NC Burggraaf J D JD Dekker H H Eijk P P PP Ylstra B B Verhoef C C Meijer G A GA Buffart T E TE Verheul H M W HM
Oncogenesis 20151005
MicroRNAs (miRs) have been recognized as promising biomarkers. It is unknown to what extent tumor-derived miRs are differentially expressed between primary colorectal cancers (pCRCs) and metastatic lesions, and to what extent the expression profiles of tumor tissue differ from the surrounding normal tissue. Next-generation sequencing (NGS) of 220 fresh-frozen samples, including paired primary and metastatic tumor tissue and non-tumorous tissue from 38 patients, revealed expression of 2245 known ...[more]
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