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Dataset Information

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University Medical Centre Groningen


ABSTRACT: Organisation EGAO00000000286

PROVIDER: EGAO00000000286 | EGA |

REPOSITORIES: EGA

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Publications

Evaluation of European coeliac disease risk variants in a north Indian population.

Senapati Sabyasachi S   Gutierrez-Achury Javier J   Sood Ajit A   Midha Vandana V   Szperl Agata A   Romanos Jihane J   Zhernakova Alexandra A   Franke Lude L   Alonso Santos S   Thelma B K BK   Wijmenga Cisca C   Trynka Gosia G  

European journal of human genetics : EJHG 20140723 4


Studies in European populations have contributed to a better understanding of the genetics of complex diseases, for example, in coeliac disease (CeD), studies of over 23 000 European samples have reported association to the HLA locus and another 39 loci. However, these associations have not been evaluated in detail in other ethnicities. We sought to better understand how disease-associated loci that have been mapped in Europeans translate to a disease risk for a population with a different ethni  ...[more]

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