Dataset Information
The Institute of Cancer Research
Ontology highlight
ABSTRACT:
PROVIDER: EGAO00000000404 | EGA |
REPOSITORIES: EGA
Publications
Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer.
Oncotarget 20161101 44
The tumor microenvironment is pivotal in influencing cancer progression and metastasis. Different cells co-exist with high spatial diversity within a patient, yet their combinatorial effects are poorly understood. We investigate the similarity of the tumor microenvironment of 192 local metastatic lesions in 61 ovarian cancer patients. An ecologically inspired measure of microenvironmental diversity derived from multiple metastasis sites is correlated with clinicopathological characteristics and ...[more]
