Dataset Information

EBI and CRG

ABSTRACT: Organisation EGAO00000000791

PROVIDER: EGAO00000000791 | EGA |

REPOSITORIES: EGA

ACCESS DATA

Publications

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Wahl Simone S Drong Alexander A Lehne Benjamin B Loh Marie M Scott William R WR Kunze Sonja S Tsai Pei-Chien PC Ried Janina S JS Zhang Weihua W Yang Youwen Y Tan Sili S Fiorito Giovanni G Franke Lude L Guarrera Simonetta S Kasela Silva S Kriebel Jennifer J Richmond Rebecca C RC Adamo Marco M Afzal Uzma U Ala-Korpela Mika M Albetti Benedetta B Ammerpohl Ole O Apperley Jane F JF Beekman Marian M Bertazzi Pier Alberto PA Black S Lucas SL Blancher Christine C Bonder Marc-Jan MJ Brosch Mario M Carstensen-Kirberg Maren M de Craen Anton J M AJ de Lusignan Simon S Dehghan Abbas A Elkalaawy Mohamed M Fischer Krista K Franco Oscar H OH Gaunt Tom R TR Hampe Jochen J Hashemi Majid M Isaacs Aaron A Jenkinson Andrew A Jha Sujeet S Kato Norihiro N Krogh Vittorio V Laffan Michael M Meisinger Christa C Meitinger Thomas T Mok Zuan Yu ZY Motta Valeria V Ng Hong Kiat HK Nikolakopoulou Zacharoula Z Nteliopoulos Georgios G Panico Salvatore S Pervjakova Natalia N Prokisch Holger H Rathmann Wolfgang W Roden Michael M Rota Federica F Rozario Michelle Ann MA Sandling Johanna K JK Schafmayer Clemens C Schramm Katharina K Siebert Reiner R Slagboom P Eline PE Soininen Pasi P Stolk Lisette L Strauch Konstantin K Tai E-Shyong ES Tarantini Letizia L Thorand Barbara B Tigchelaar Ettje F EF Tumino Rosario R Uitterlinden Andre G AG van Duijn Cornelia C van Meurs Joyce B J JB Vineis Paolo P Wickremasinghe Ananda Rajitha AR Wijmenga Cisca C Yang Tsun-Po TP Yuan Wei W Zhernakova Alexandra A Batterham Rachel L RL Smith George Davey GD Deloukas Panos P Heijmans Bastiaan T BT Herder Christian C Hofman Albert A Lindgren Cecilia M CM Milani Lili L van der Harst Pim P Peters Annette A Illig Thomas T Relton Caroline L CL Waldenberger Melanie M Järvelin Marjo-Riitta MR Bollati Valentina V Soong Richie R Spector Tim D TD Scott James J McCarthy Mark I MI Elliott Paul P Bell Jordana T JT Matullo Giuseppe G Gieger Christian C Kooner Jaspal S JS Grallert Harald H Chambers John C JC

Nature 20161221 7635

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of developing type 2 diabetes, cardiovascular disease and related metabolic and inflammatory disturbances. Although the mechanisms linking adiposity to associated clinical conditions are poorly understood, recent studies suggest that adiposity may influence DNA methylation, a key regulator of gene expression and molecular phenotype. Here we use epigenome-wide association to show that body mass index ...[more]

PMID: 28002404

Publication: 1/2

Dataset Information

EBI and CRG

Publications

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets