Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

7 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 1000

Radboud university medical center, Radboud Institute for Health Sciences

ABSTRACT: Organisation EGAO00000001244

PROVIDER: EGAO00000001244 | EGA |

REPOSITORIES: EGA

ACCESS DATA

Json Xml

Similar Datasets

Radboud University medical center

Project description:Organisation EGAO00000000441

| EGAO00000000441 | EGA

Columbia University Irving Medical Center RNASeq of meningioma tumors

Project description:We use a Master Regular-based precision cancer medicine framework to predict drug sensitivity to tumors.

2022-09-06 | GSE212377 | GEO

Modeling and simulation in medical sciences: an overview of specific applications based on research experience in EMRI (Endocrinology and Metabolism Research Institute of Tehran University of Medical Sciences).

Project description:The concomitant use of various types of models (in silico, in vitro, and in vivo) has been exemplified here within the context of biomedical researches performed in the Endocrinology and Metabolism Research Institute (EMRI) of Tehran University of Medical Sciences. Two main research aeras have been discussed: the search for new small molecules as therapeutics for diabetes and related metabolic conditions, and diseases related to protein aggregation. Due to their multidisciplinary nature, the majority of these studies have needed the collaboration of different specialties. In both cases, a brief overview of the subject is provided through literature examples, and sequential use of these methods is described.

| S-EPMC7821172 | biostudies-literature

Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen,

Project description:Organisation EGAO00000000859

| EGAO00000000859 | EGA

The P50 Research Center in Perioperative Sciences: How the investment by the National Institute of General Medical Sciences in team science has reduced postburn mortality.

Project description:Since the inception of the P50 Research Center in Injury and Peri-operative Sciences (RCIPS) funding mechanism, the National Institute of General Medical Sciences has supported a team approach to science. Many advances in critical care, particularly burns, have been driven by RCIPS teams. In fact, burns that were fatal in the early 1970s, prior to the inception of the P50 RCIPS program, are now routinely survived as a result of the P50-funded research. The advances in clinical care that led to the reduction in postburn death were made by optimizing resuscitation, incorporating early excision and grafting, bolstering acute care including support for inhalation injury, modulating the hypermetabolic response, augmenting the immune response, incorporating aerobic exercise, and developing antiscarring strategies. The work of the Burn RCIPS programs advanced our understanding of the pathophysiologic response to burn injury. As a result, the effects of a large burn on all organ systems have been studied, leading to the discovery of persistent dysfunction, elucidation of the underlying molecular mechanisms, and identification of potential therapeutic targets. Survival and subsequent patient satisfaction with quality of life have increased. In this review article, we describe the contributions of the Galveston P50 RCIPS that have changed postburn care and have considerably reduced postburn mortality.

| S-EPMC5573648 | biostudies-literature

Erasmus University Medical Center

Project description:Organisation EGAO00000001053

| EGAO00000001053 | EGA

University Medical Center Utrecht

Project description:Organisation EGAO00000001038

| EGAO00000001038 | EGA

Leiden University Medical Center

Project description:Organisation EGAO00000000220

| EGAO00000000220 | EGA

VU University medical center

Project description:Organisation EGAO00000000688