Genomics

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APCDR AGV Project: WGS of an Ugandan population

ABSTRACT: The African Genome Variation Project (AGVP) provides a resource to help design, implement and interpret genomic studies in sub-Saharan Africa (SSA) and worldwide. The AGVP represents dense genotypes from 1,481 and whole genome sequences (WGS) from 320 individuals across SSA. As part of the AGVP we sequenced the genome of 100 unrelated Baganda from rural Uganda to about 4x depth.

PROVIDER: EGAS00001000363 | EGA |

REPOSITORIES: EGA

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The African Genome Variation Project shapes medical genetics in Africa.

Gurdasani Deepti D   Carstensen Tommy T   Tekola-Ayele Fasil F   Pagani Luca L   Tachmazidou Ioanna I   Hatzikotoulas Konstantinos K   Karthikeyan Savita S   Iles Louise L   Pollard Martin O MO   Choudhury Ananyo A   Ritchie Graham R S GR   Xue Yali Y   Asimit Jennifer J   Nsubuga Rebecca N RN   Young Elizabeth H EH   Pomilla Cristina C   Kivinen Katja K   Rockett Kirk K   Kamali Anatoli A   Doumatey Ayo P AP   Asiki Gershim G   Seeley Janet J   Sisay-Joof Fatoumatta F   Jallow Muminatou M   Tollman Stephen S   Mekonnen Ephrem E   Ekong Rosemary R   Oljira Tamiru T   Bradman Neil N   Bojang Kalifa K   Ramsay Michele M   Adeyemo Adebowale A   Bekele Endashaw E   Motala Ayesha A   Norris Shane A SA   Pirie Fraser F   Kaleebu Pontiano P   Kwiatkowski Dominic D   Tyler-Smith Chris C   Rotimi Charles C   Zeggini Eleftheria E   Sandhu Manjinder S MS  

Nature 20141203 7534

Given the importance of Africa to studies of human origins and disease susceptibility, detailed characterization of African genetic diversity is needed. The African Genome Variation Project provides a resource with which to design, implement and interpret genomic studies in sub-Saharan Africa and worldwide. The African Genome Variation Project represents dense genotypes from 1,481 individuals and whole-genome sequences from 320 individuals across sub-Saharan Africa. Using this resource, we find  ...[more]

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