Genomics

Dataset Information

0

GWAS data (Illumina 2.5 M SNPs) in Cuban cohorts of dengue disease


ABSTRACT: We will have 274 individuals typed for the Illumina Human Omni 2.5 chip. The individuals are from two locations in Cuba (Havana and Guantanamo) and from four phenotype classes (asymptomatic, control dengue fever and dengue hemorrhagic fever).

PROVIDER: EGAS00001002276 | EGA |

REPOSITORIES: EGA

altmetric image

Publications


Ethnic groups can display differential genetic susceptibility to infectious diseases. The arthropod-born viral dengue disease is one such disease, with empirical and limited genetic evidence showing that African ancestry may be protective against the haemorrhagic phenotype. Global ancestry analysis based on high-throughput genotyping in admixed populations can be used to test this hypothesis, while admixture mapping can map candidate protective genes. A Cuban dengue fever cohort was genotyped us  ...[more]

Similar Datasets

2010-11-20 | E-GEOD-25226 | biostudies-arrayexpress
2018-07-31 | GSE96656 | GEO
2011-12-31 | E-GEOD-28405 | biostudies-arrayexpress
| EGAD00010001487 | EGA
2013-09-06 | E-GEOD-50634 | biostudies-arrayexpress
2021-09-21 | GSE174482 | GEO
2010-09-01 | E-GEOD-18090 | biostudies-arrayexpress
2023-04-13 | GSE215835 | GEO
2022-02-16 | E-MTAB-9467 | biostudies-arrayexpress
| EGAS00001002756 | EGA